Literature DB >> 11436175

Preliminary report: Amino acid profile in platelets of diabetic patients.

G De Luca1, P R Calpona, A Caponetti, V Macaione, A Di Benedetto, D Cucinotta, R M Di Giorgio.   

Abstract

Platelet levels of 19 amino acids were measured in 20 outpatients with type 1 (age [mean +/- SE], 35.5 +/- 2.0 years) and 27 with type 2 (age, 58.4 +/- 1.4 years) diabetes, and 20 young (age 33.7 +/- 1.3 years) and 20 older (age 57.4 +/- 1.5 years) healthy volunteers. Platelet levels of most amino acids tended to be lower in patients with type 1 diabetes than in healthy controls. In particular, asparagine, glycine, taurine, alanine, valine, cysteine, leucine, phenylalanine, and lysine levels, expressed as nmol/10(8) platelets, were significantly lower. Only taurine significantly decreased in patients with type 2 diabetes, whereas threonine, alanine, and isoleucine increased. Copyright 2001 by W.B. Saunders Company

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Year:  2001        PMID: 11436175     DOI: 10.1053/meta.2001.24193

Source DB:  PubMed          Journal:  Metabolism        ISSN: 0026-0495            Impact factor:   8.694


  9 in total

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Authors:  Kayoko Esaki; Tomoko Sayano; Chiaki Sonoda; Takumi Akagi; Takeshi Suzuki; Takuya Ogawa; Masahiro Okamoto; Takeo Yoshikawa; Yoshio Hirabayashi; Shigeki Furuya
Journal:  J Biol Chem       Date:  2015-04-22       Impact factor: 5.157

2.  Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine.

Authors:  Rajagopal V Sekhar; Siripoom V McKay; Sanjeet G Patel; Anuradha P Guthikonda; Vasumathi T Reddy; Ashok Balasubramanyam; Farook Jahoor
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Review 3.  Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease.

Authors:  Giuseppe Verdile; Kevin N Keane; Vinicius F Cruzat; Sandra Medic; Miheer Sabale; Joanne Rowles; Nadeeja Wijesekara; Ralph N Martins; Paul E Fraser; Philip Newsholme
Journal:  Mediators Inflamm       Date:  2015-11-26       Impact factor: 4.711

Review 4.  Diabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stress.

Authors:  Sergio Rosales-Corral; Dun-Xian Tan; Lucien Manchester; Russel J Reiter
Journal:  Oxid Med Cell Longev       Date:  2015-02-26       Impact factor: 6.543

5.  Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.

Authors:  Yunpeng Ding; Gard F T Svingen; Eva R Pedersen; Jesse F Gregory; Per M Ueland; Grethe S Tell; Ottar K Nygård
Journal:  J Am Heart Assoc       Date:  2015-12-31       Impact factor: 5.501

6.  A Combined Metabolomic and Proteomic Analysis of Gestational Diabetes Mellitus.

Authors:  Joanna Hajduk; Agnieszka Klupczynska; Paweł Dereziński; Jan Matysiak; Piotr Kokot; Dorota M Nowak; Marzena Gajęcka; Ewa Nowak-Markwitz; Zenon J Kokot
Journal:  Int J Mol Sci       Date:  2015-12-16       Impact factor: 5.923

7.  Association of serum glycine levels with metabolic syndrome in an elderly Chinese population.

Authors:  Xianghui Li; Liang Sun; Wenduo Zhang; Hongxia Li; Siming Wang; Hongna Mu; Qi Zhou; Ying Zhang; Yueming Tang; Yu Wang; Wenxiang Chen; Ruiyue Yang; Jun Dong
Journal:  Nutr Metab (Lond)       Date:  2018-12-17       Impact factor: 4.169

8.  Arsenic Exposure from Drinking Water and Urinary Metabolomics: Associations and Long-Term Reproducibility in Bangladesh Adults.

Authors:  Fen Wu; Liang Chi; Hongyu Ru; Faruque Parvez; Vesna Slavkovich; Mahbub Eunus; Alauddin Ahmed; Tariqul Islam; Muhammad Rakibuz-Zaman; Rabiul Hasan; Golam Sarwar; Joseph H Graziano; Habibul Ahsan; Kun Lu; Yu Chen
Journal:  Environ Health Perspect       Date:  2018-01-12       Impact factor: 11.035

9.  A multi-omics investigation of the molecular characteristics and classification of six metabolic syndrome relevant diseases.

Authors:  Di Chen; Xinjie Zhao; Zhigang Sui; Huan Niu; Luonan Chen; Cheng Hu; Qiuhui Xuan; Xuhong Hou; Rong Zhang; Lina Zhou; Yanli Li; Huiming Yuan; Yukui Zhang; Jiarui Wu; Lihua Zhang; Ren'an Wu; Hai-Long Piao; Guowang Xu; Weiping Jia
Journal:  Theranostics       Date:  2020-01-12       Impact factor: 11.556

  9 in total

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