Literature DB >> 11435706

Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes.

K Ogura1, K Matsumoto, A Kuroiwa, T Isobe, T Otoguro, V Jurecic, A Baldini, Y Matsuda, T Ogura.   

Abstract

Three highly homologous homeobox genes (caupolican, araucan and mirror) have been identified in Drosophila. These genes belong to the novel Iroquois complex, which acts as a pre-pattern molecule in Drosophila neurogenesis. Recently several vertebrate Iroquois homologues (Irx) were isolated and found to be involved in pattern formation of various tissues. Here we report cytogenetic mapping of four human and five chicken Iroquois genes by FISH. Our findings revealed that vertebrate Irx genes are clustered at two different loci. Copyright 2001 S. Karger AG, Basel.

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Year:  2001        PMID: 11435706     DOI: 10.1159/000056921

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  5 in total

1.  A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts.

Authors:  Elisa de la Calle-Mustienes; Cármen Gloria Feijóo; Miguel Manzanares; Juan J Tena; Elisa Rodríguez-Seguel; Annalisa Letizia; Miguel L Allende; José Luis Gómez-Skarmeta
Journal:  Genome Res       Date:  2005-07-15       Impact factor: 9.043

2.  Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

Authors:  Laura A McDonald; Dianne Gerrelli; Yvonne Fok; Laurence D Hurst; Cheryll Tickle
Journal:  J Anat       Date:  2010-04-14       Impact factor: 2.610

3.  Organization of Iroquois genes in fish.

Authors:  Renate Dildrop; Ulrich Rüther
Journal:  Dev Genes Evol       Date:  2004-05-06       Impact factor: 0.900

4.  Evaluation of IRX Genes and Conserved Noncoding Elements in a Region on 5p13.3 Linked to Families with Familial Idiopathic Scoliosis and Kyphosis.

Authors:  Cristina M Justice; Kevin Bishop; Blake Carrington; Jim C Mullikin; Kandice Swindle; Beth Marosy; Raman Sood; Nancy H Miller; Alexander F Wilson
Journal:  G3 (Bethesda)       Date:  2016-06-01       Impact factor: 3.154

5.  Iroquois Homeobox 1 Acts as a True Tumor Suppressor in Multiple Organs by Regulating Cell Cycle Progression.

Authors:  In Hye Jung; Dawoon E Jung; Yong-Yoon Chung; Kyung-Sik Kim; Seung Woo Park
Journal:  Neoplasia       Date:  2019-08-23       Impact factor: 5.715

  5 in total

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