Literature DB >> 11435657

Cerebellar atrophy in an epileptic child: is it due to phenytoin?

S R Ahuja1, S Karande, M V Kulkarni.   

Abstract

A four and half year old epileptic child on phenytoin therapy since one year presented with signs of cerebellar dysfunction. Serum phenytoin level was high (33 mcg/ml) and computerised tomographic scan of the brain showed severe generalised cerebellar atrophy. The cerebellar signs represented drug over dosage and toxicity and persisted long after omission of phenytoin.

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Year:  2000        PMID: 11435657

Source DB:  PubMed          Journal:  J Postgrad Med        ISSN: 0022-3859            Impact factor:   1.476


  1 in total

1.  Phenytoin-induced cerebellar atrophy in an epileptic boy.

Authors:  Nithin Kumar; Ananya Chakraborty; Swaroop H Suresh; Sashidharan Basappaji; Anand L Betdur
Journal:  Indian J Pharmacol       Date:  2013 Nov-Dec       Impact factor: 1.200

  1 in total

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