Literature DB >> 11435606

Deletion mapping of the encephalomyocarditis virus primary cleavage site.

H Hahn1, A C Palmenberg.   

Abstract

The cotranslational, primary self-cleavage reaction of cardiovirus polyprotein relies on a highly conserved, short segment of amino acids at the 2A-2B protein boundary. The amino terminus of the required element for encephalomyocarditis virus has now been mapped to include Tyr(126) of the 2A protein, the 18th amino acid before the cleavage site.

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Year:  2001        PMID： 11435606      PMCID： PMC114454          DOI： 10.1128/JVI.75.15.7215-7218.2001

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  15 in total

Review 1.  Proteolytic processing of picornaviral polyprotein.

Authors:  A C Palmenberg
Journal:  Annu Rev Microbiol       Date:  1990       Impact factor: 15.500

2.  Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein.

Authors:  D A Matthews; W W Smith; R A Ferre; B Condon; G Budahazi; W Sisson; J E Villafranca; C A Janson; H E McElroy; C L Gribskov
Journal:  Cell       Date:  1994-06-03       Impact factor: 41.582

3.  Products of the porcine group C rotavirus NSP3 gene bind specifically to double-stranded RNA and inhibit activation of the interferon-induced protein kinase PKR.

Authors:  J O Langland; S Pettiford; B Jiang; B L Jacobs
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

4.  Mutational analysis of the encephalomyocarditis virus primary cleavage.

Authors:  H Hahn; A C Palmenberg
Journal:  J Virol       Date:  1996-10       Impact factor: 5.103

5.  Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release.

Authors:  F J van Kuppeveld; J G Hoenderop; R L Smeets; P H Willems; H B Dijkman; J M Galama; W J Melchers
Journal:  EMBO J       Date:  1997-06-16       Impact factor: 11.598

6.  The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition.

Authors:  E M Bergmann; S C Mosimann; M M Chernaia; B A Malcolm; M N James
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

7.  The cleavage activities of aphthovirus and cardiovirus 2A proteins.

Authors:  M L Donnelly; D Gani; M Flint; S Monaghan; M D Ryan
Journal:  J Gen Virol       Date:  1997-01       Impact factor: 3.891

8.  Mengo virus 3C proteinase: recombinant expression, intergenus substrate cleavage and localization in vivo.

Authors:  D J Hall; A C Palmenberg
Journal:  Virus Genes       Date:  1996       Impact factor: 2.332

9.  The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase.

Authors:  A Haghighat; Y Svitkin; I Novoa; E Kuechler; T Skern; N Sonenberg
Journal:  J Virol       Date:  1996-12       Impact factor: 5.103

10.  Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus.

Authors:  Y V Svitkin; H Hahn; A C Gingras; A C Palmenberg; N Sonenberg
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103
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  10 in total

1.  Theiler's murine encephalomyelitis virus contrasts with encephalomyocarditis and foot-and-mouth disease viruses in its functional utilization of the StopGo non-standard translation mechanism.

Authors:  G Loughran; J E Libbey; S Uddowla; M F Scallan; M D Ryan; R S Fujinami; E Rieder; J F Atkins
Journal:  J Gen Virol       Date:  2012-10-24       Impact factor: 3.891

2.  Mutational analysis of the EMCV 2A protein identifies a nuclear localization signal and an eIF4E binding site.

Authors:  Rachel Groppo; Bradley A Brown; Ann C Palmenberg
Journal:  Virology       Date:  2010-12-09       Impact factor: 3.616

3.  Encephalomyocarditis virus 2A protein is required for viral pathogenesis and inhibition of apoptosis.

Authors:  M Carocci; N Cordonnier; H Huet; A Romey; A Relmy; K Gorna; S Blaise-Boisseau; S Zientara; L Bakkali Kassimi
Journal:  J Virol       Date:  2011-08-17       Impact factor: 5.103

4.  Ribosomal frameshifting into an overlapping gene in the 2B-encoding region of the cardiovirus genome.

Authors:  Gary Loughran; Andrew E Firth; John F Atkins
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-24       Impact factor: 11.205

5.  Molecular analysis of three Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins.

Authors:  Susanne Johansson; Bo Niklasson; Jacob Maizel; Alexander E Gorbalenya; A Michael Lindberg
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

6.  Cardiovirus 2A protein associates with 40S but not 80S ribosome subunits during infection.

Authors:  Rachel Groppo; Ann C Palmenberg
Journal:  J Virol       Date:  2007-08-29       Impact factor: 5.103

Review 7.  The encephalomyocarditis virus.

Authors:  Margot Carocci; Labib Bakkali-Kassimi
Journal:  Virulence       Date:  2012-06-22       Impact factor: 5.882

8.  2A peptides provide distinct solutions to driving stop-carry on translational recoding.

Authors:  Pamila Sharma; Fu Yan; Victoria A Doronina; Helena Escuin-Ordinas; Martin D Ryan; Jeremy D Brown
Journal:  Nucleic Acids Res       Date:  2011-12-02       Impact factor: 16.971

9.  Characterization of Ribosomal Frameshifting in Theiler's Murine Encephalomyelitis Virus.

Authors:  Leanne K Finch; Roger Ling; Sawsan Napthine; Allan Olspert; Thomas Michiels; Cécile Lardinois; Susanne Bell; Gary Loughran; Ian Brierley; Andew E Firth
Journal:  J Virol       Date:  2015-08       Impact factor: 5.103

10.  Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch.

Authors:  Chris H Hill; Lukas Pekarek; Sawsan Napthine; Anuja Kibe; Andrew E Firth; Stephen C Graham; Neva Caliskan; Ian Brierley
Journal:  Nat Commun       Date:  2021-12-09       Impact factor: 14.919
  10 in total

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