Literature DB >> 11434919

West Nile virus-induced bax-dependent apoptosis.

M C Parquet1, A Kumatori, F Hasebe, K Morita, A Igarashi.   

Abstract

The mechanism of cell death induced by West Nile virus (WNV), a causative agent of human febrile syndrome and encephalitis, was investigated. WNV-infected K562 and Neuro-2a cells manifested the typical features of apoptosis, including cell shrinkage, chromatin condensation and subdiploid DNA content by flow cytometry. DNA fragmentation into nucleosomal size and changes in outer cell membrane phospholipid composition were also observed in K562 cells. UV-inactivated virus failed to induce the above-mentioned characteristics, suggesting that viral replication may be required for the induction of apoptosis by WNV. Additionally, signals involved in WNV-induced apoptosis are associated with the up-regulation of bax gene expression.

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Year:  2001        PMID： 11434919     DOI： 10.1016/s0014-5793(01)02573-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  55 in total

1.  Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication.

Authors:  W Li; Y Li; N Kedersha; P Anderson; M Emara; K M Swiderek; G T Moreno; M A Brinton
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

2.  West Nile virus-induced neuroinflammation: glial infection and capsid protein-mediated neurovirulence.

Authors:  Guido van Marle; Joseph Antony; Heather Ostermann; Christopher Dunham; Tracey Hunt; William Halliday; Ferdinand Maingat; Matt D Urbanowski; Tom Hobman; James Peeling; Christopher Power
Journal:  J Virol       Date:  2007-08-01       Impact factor: 5.103

Review 3.  Pathogenesis of West Nile Virus infection: a balance between virulence, innate and adaptive immunity, and viral evasion.

Authors:  Melanie A Samuel; Michael S Diamond
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

Review 4.  West Nile virus: A re-emerging pathogen revisited.

Authors:  Miguel A Martín-Acebes; Juan-Carlos Saiz
Journal:  World J Virol       Date:  2012-04-12

Review 5.  Regulation of cell survival and death during Flavivirus infections.

Authors:  Sounak Ghosh Roy; Beata Sadigh; Emmanuel Datan; Richard A Lockshin; Zahra Zakeri
Journal:  World J Biol Chem       Date:  2014-05-26

6.  Differential effects of mutations in NS4B on West Nile virus replication and inhibition of interferon signaling.

Authors:  Jared D Evans; Christoph Seeger
Journal:  J Virol       Date:  2007-08-22       Impact factor: 5.103

7.  Flock house virus induces apoptosis by depletion of Drosophila inhibitor-of-apoptosis protein DIAP1.

Authors:  Erik W Settles; Paul D Friesen
Journal:  J Virol       Date:  2007-11-07       Impact factor: 5.103

8.  Swine acute diarrhea syndrome coronavirus-induced apoptosis is caspase- and cyclophilin D- dependent.

Authors:  Jiyu Zhang; Yuru Han; Hongyan Shi; Jianfei Chen; Xin Zhang; Xiaobo Wang; Ling Zhou; Jianbo Liu; Jialin Zhang; Zhaoyang Ji; Zhaoyang Jing; Jingyun Ma; Da Shi; Li Feng
Journal:  Emerg Microbes Infect       Date:  2020-02-24       Impact factor: 7.163

9.  Pro-inflammatory cytokines derived from West Nile virus (WNV)-infected SK-N-SH cells mediate neuroinflammatory markers and neuronal death.

Authors:  Mukesh Kumar; Saguna Verma; Vivek R Nerurkar
Journal:  J Neuroinflammation       Date:  2010-10-31       Impact factor: 8.322

Review 10.  West Nile virus and its emergence in the United States of America.

Authors:  Kristy O Murray; Eva Mertens; Philippe Despres
Journal:  Vet Res       Date:  2010 Nov-Dec       Impact factor: 3.683
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