Literature DB >> 11433880

Lithium revisited: savings brought about by the use of lithium, 1970-1991.

R J Wyatt1, I D Henter, J C Jamison.   

Abstract

BACKGROUND: Recent estimates of the cost of manic-depressive illness totaled roughly $45 billion in 1991. Using data from the Epidemiological Catchment Area (ECA) study, this study estimates the savings brought about by the use of lithium between 1970 and 1991.
METHODS: Total savings are the difference between estimated actual costs and projected costs had lithium never been introduced. Actual yearly costs were interpolated from data for 1970 and 1991, and projected costs were obtained by adjusting 1970 costs with Consumer Price Index (CPI) and population inflaters. All costs for 1970 were obtained using methods almost identical to those used to calculate the 1991 costs of manic-depressive illness, presented in a previous publication. All savings are presented in 1991 dollars.
RESULTS: Between 1970 and 1991, lithium saved over $170 billion, or roughly over $8 billion per year. Approximately $15 billion in direct costs, which included inpatient and outpatient care as well as research, was saved between 1970 and 1991. The savings are more dramatic for indirect costs, which include the lost productivity of wage-earners, homemakers, family caregivers, and individuals who are in institutions or who committed suicide; these totaled roughly $155 billion.
CONCLUSIONS: Our results suggest that, although manic-depressive illness is still costly, lithium has been tremendously successful in treating the illness, and has provided enormous financial savings in the process.

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Year:  2001        PMID: 11433880      PMCID: PMC4302724          DOI: 10.1023/a:1010319610021

Source DB:  PubMed          Journal:  Psychiatr Q        ISSN: 0033-2720


  23 in total

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Authors:  G E Simon; J Unützer
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Journal:  Lancet       Date:  1971-06-26       Impact factor: 79.321

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Journal:  Am J Psychiatry       Date:  1994-12       Impact factor: 18.112

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Authors:  J R Calabrese; S H Fatemi; M Kujawa; M J Woyshville
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Authors:  W E Narrow; D A Regier; D S Rae; R W Manderscheid; B Z Locke
Journal:  Arch Gen Psychiatry       Date:  1993-02

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Authors:  P Vestergaard; J Aagaard
Journal:  J Affect Disord       Date:  1991-01       Impact factor: 4.839

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Authors:  R J Wyatt; I Henter
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  2 in total

Review 1.  Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics.

Authors:  M Alda
Journal:  Mol Psychiatry       Date:  2015-02-17       Impact factor: 15.992

2.  A 7 Tesla Amygdalar-Hippocampal Shape Analysis of Lithium Response in Bipolar Disorder.

Authors:  Thomas L Athey; Can Ceritoglu; Daniel J Tward; Kwame S Kutten; J Raymond DePaulo; Kara Glazer; Fernando S Goes; John R Kelsoe; Francis Mondimore; Caroline M Nievergelt; Kelly Rootes-Murdy; Peter P Zandi; J Tilak Ratnanather; Pamela B Mahon
Journal:  Front Psychiatry       Date:  2021-02-16       Impact factor: 4.157

  2 in total

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