Literature DB >> 11431570

Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice.

V Mack1, N Burnashev, K M Kaiser, A Rozov, V Jensen, O Hvalby, P H Seeburg, B Sakmann, R Sprengel.   

Abstract

Plasticity of mature hippocampal CA1 synapses is dependent on l-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR-A) subunit. In GluR-A-deficient mice, plasticity could be restored by controlled expression of green fluorescent protein (GFP)-tagged GluR-A, which contributes to channel formation and displayed the developmental redistribution of AMPA receptors in CA1 pyramidal neurons. Long-term potentiation (LTP) induced by pairing or tetanic stimulation was rescued in adult GluR-A(-/-) mice when (GFP)GluR-A expression was constitutive or induced in already fully developed pyramidal cells. This shows that GluR-A-independent forms of synaptic plasticity can mediate the establishment of mature hippocampal circuits that are prebuilt to express GluR-A-dependent LTP.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11431570     DOI： 10.1126/science.1059365

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  48 in total

Review 1.  Restless AMPA receptors: implications for synaptic transmission and plasticity.

Authors:  C Lüscher; M Frerking
Journal:  Trends Neurosci       Date:  2001-11       Impact factor: 13.837

2.  Molecular dissection of hippocampal theta-burst pairing potentiation.

Authors:  D A Hoffman; R Sprengel; B Sakmann
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-28       Impact factor: 11.205

Review 3.  AMPA receptor trafficking and long-term potentiation.

Authors:  Roberto Malinow
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2003-04-29       Impact factor: 6.237

4.  Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain.

Authors:  Huimin Wang; Eiji Shimizu; Ya-Ping Tang; Min Cho; Maureen Kyin; Wenqi Zuo; Daphne A Robinson; Peter J Alaimo; Chao Zhang; Hiromi Morimoto; Min Zhuo; Ruiben Feng; Kevan M Shokat; Joe Z Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-19       Impact factor: 11.205

5.  In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy.

Authors:  Juergen C Jung; Amit D Mehta; Emre Aksay; Raymond Stepnoski; Mark J Schnitzer
Journal:  J Neurophysiol       Date:  2004-05-05       Impact factor: 2.714

6.  Changes in AMPA receptor currents following LTP induction on rat CA1 pyramidal neurones.

Authors:  Bertalan K Andrásfalvy; Jeffrey C Magee
Journal:  J Physiol       Date:  2004-07-02       Impact factor: 5.182

7.  The effects of GluA1 deletion on the hippocampal population code for position.

Authors:  Evgeny Resnik; James M McFarland; Rolf Sprengel; Bert Sakmann; Mayank R Mehta
Journal:  J Neurosci       Date:  2012-06-27       Impact factor: 6.167

Review 8.  Glutamate receptor ion channels: structure, regulation, and function.

Authors:  Stephen F Traynelis; Lonnie P Wollmuth; Chris J McBain; Frank S Menniti; Katie M Vance; Kevin K Ogden; Kasper B Hansen; Hongjie Yuan; Scott J Myers; Ray Dingledine
Journal:  Pharmacol Rev       Date:  2010-09       Impact factor: 25.468

9.  Epileptiform activity in rat hippocampus strengthens excitatory synapses.

Authors:  Mathias H Abegg; Natasa Savic; Markus U Ehrengruber; R Anne McKinney; Beat H Gähwiler
Journal:  J Physiol       Date:  2003-10-31       Impact factor: 5.182

10.  State-dependent Ras signaling and AMPA receptor trafficking.

Authors:  Yi Qin; Yinghua Zhu; Joel P Baumgart; Ruth L Stornetta; Kenneth Seidenman; Volker Mack; Linda van Aelst; J Julius Zhu
Journal:  Genes Dev       Date:  2005-08-17       Impact factor: 11.361
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.