| Literature DB >> 11430013 |
H R Bokesch1, L K Pannell, P K Cochran, R C Sowder, T C McKee, M R Boyd.
Abstract
A 37 amino acid cyclic polypeptide has been isolated from the organic extract of the tropical tree Palicourea condensata. Palicourein (1) is the largest of a growing family of plant peptides that contain a cyclized amino acid backbone cross-linked via three internal disulfide bridges. Palicourein inhibits the in vitro cytopathic effects of HIV-1RF infection of CEM-SS cells with an EC50 value of 0.1 microM and an IC50 value of 1.5 microM.Entities:
Mesh：
Substances：
Year: 2001 PMID： 11430013 DOI： 10.1021/np000372l
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050