Literature DB >> 11429870

Exploring a benzyloxyaniline linker utilizing ceric ammonium nitrate (CAN) as a cleavage reagent: solid-phase synthesis of N-unsubstituted beta-lactams and secondary amides.

K H Gordon1, S Balasubramanian.   

Abstract

[figure: see text] A novel benzyloxyaniline linker that uses ceric ammonium nitrate (CAN) as a cleavage reagent is described. Its application in the solid-phase synthesis of N-unsubstituted beta-lactams and secondary amides furnishes compounds in moderate to excellent yield (45-91%) and high purity (93-99%).

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Year:  2001        PMID： 11429870     DOI： 10.1021/ol006766l

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Synthesis of Oligosaccharide Components of the Outer Core Domain of P. aeruginosa Lipopolysaccharide Using a Multifunctional Hydroquinone-Derived Reducing-End Capping Group.

Authors:  Abhishek Vartak; Fatma M Hefny; Steven J Sucheck
Journal:  Org Lett       Date:  2017-12-29       Impact factor: 6.005

2.  Synthesis of novel N-(4-ethoxyphenyl) azetidin-2-ones and their oxidative N-deprotection by ceric ammonium nitrate.

Authors:  Aliasghar Jarrahpour; Maaroof Zarei
Journal:  Molecules       Date:  2007-10-25       Impact factor: 4.411

3.  Exploring solid-phase approaches for the preparation of new beta-lactams from amino acids.

Authors:  Guillermo Gerona-Navarro; Miriam Royo; Ma Teresa García-López; Fernando Albericio; Rosario González-Muñiz
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943
  3 in total

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