Literature DB >> 11429616

The effect of acidosis on the ECG of the rat heart.

A Aberra1, K Komukai, F C Howarth, C H Orchard.   

Abstract

We have investigated the effect of acidosis on the ECG in isolated rat heart to determine whether acidosis has marked effects on the ECG, and have used pharmacological agents to investigate possible mechanisms whereby acidosis alters the ECG. Acidosis produced a marked decrease in heart rate and an increase in P-R interval with little apparent effect on the duration of the QRS complex. The effects of acidosis did not appear to be due to acidosis-induced changes in transmitter release from severed autonomic nerve terminals within the heart. Experimental Physiology (2001) 86.1, 27-31.

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Year:  2001        PMID： 11429616     DOI： 10.1113/eph8602051

Source DB:  PubMed          Journal:  Exp Physiol        ISSN： 0958-0670            Impact factor:   2.969


  7 in total

1.  Systemic acid load from the diet affects maximal-exercise RER.

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2.  Acute electrocardiographic ST segment elevation may predict hypotension in a swine model of severe cyanide toxicity.

Authors:  Tylan A Muncy; Vikhyat S Bebarta; Shawn M Varney; Rebecca Pitotti; Susan Boudreau
Journal:  J Med Toxicol       Date:  2012-09

3.  Mechano-electric feedback in the fish heart.

Authors:  Simon M Patrick; Ed White; Holly A Shiels
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Journal:  Stem Cells Int       Date:  2018-01-08       Impact factor: 5.443

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Authors:  Florian M Trefz; Ingrid Lorenz; Peter D Constable
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Review 6.  Reevaluating methods reporting practices to improve reproducibility: an analysis of methodological rigor for the Langendorff whole heart technique.

Authors:  D Ryan King; Kathryn M Hardin; Gregory S Hoeker; Steven Poelzing
Journal:  Am J Physiol Heart Circ Physiol       Date:  2022-06-24       Impact factor: 5.125

7.  Acidosis slows electrical conduction through the atrio-ventricular node.

Authors:  Ashley M Nisbet; Francis L Burton; Nicola L Walker; Margaret A Craig; Hongwei Cheng; Jules C Hancox; Clive H Orchard; Godfrey L Smith
Journal:  Front Physiol       Date:  2014-06-25       Impact factor: 4.566
  7 in total

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