Literature DB >> 11429239

Cytoprotective role of Solanum nigrum against gentamicin-induced kidney cell (Vero cells) damage in vitro.

V Prashanth Kumar1, S Shashidhara, M M Kumar, B Y Sridhara.   

Abstract

The 50% ethanol extract of the whole plant of Solanum nigrum was tested in vitro for its cytoprotection against gentamicin-induced toxicity on Vero cells. Cytotoxicity was significantly inhibited as assessed by the Trypan blue exclusion assay and mitochondrial dehydrogenase activity (MTT) assay. The test extract also exhibited significant hydroxyl radical scavenging potential, thus suggesting its probable mechanism of cytoprotection.

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Year:  2001        PMID： 11429239     DOI： 10.1016/s0367-326x(01)00266-0

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  11 in total

1.  Protective effects of Dialium guineense pulp on aspirin-induced gastric mucosal injury in albino rats.

Authors:  Nwogo Ajuka Obasi; Chinyere Aloke; Stella Eberechukwu Obasi; Chinedu Ogbonnia Egwu; Ademola Clement Famurewa; Patience Nkemjika Ogbu
Journal:  J Appl Biomed       Date:  2021-06-10       Impact factor: 1.797

2.  Chenopodium album prevents progression of cell growth and enhances cell toxicity in human breast cancer cell lines.

Authors:  Menka Khoobchandani; B K Ojeswi; Bhavna Sharma; Man Mohan Srivastava
Journal:  Oxid Med Cell Longev       Date:  2009 Jul-Aug       Impact factor: 6.543

3.  Antioxidant and antihyperlipidemic effect of Solanum nigrum fruit extract on the experimental model against chronic ethanol toxicity.

Authors:  Vadivel Arulmozhi; Mani Krishnaveni; Kandhan Karthishwaran; Ganesan Dhamodharan; Sankaran Mirunalini
Journal:  Pharmacogn Mag       Date:  2010-02-13       Impact factor: 1.085

4.  Antioxidant effect of methanolic extract ofSolanum nigrum berries on aspirin induced gastric mucosal injury.

Authors:  Mallika Jainu; C S Shyamala Devi
Journal:  Indian J Clin Biochem       Date:  2004-01

5.  Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum.

Authors:  Akbar Nawab; Vijay S Thakur; Mohammad Yunus; Abbas Ali Mahdi; Sanjay Gupta
Journal:  Int J Mol Med       Date:  2011-11-10       Impact factor: 4.101

6.  Effect of the Administration of Solanum nigrum Fruit on Prevention of Diabetic Nephropathy in Streptozotocin-induced Diabetic Rats.

Authors:  Fariba Azarkish; Kobra Hashemi; Ardashir Talebi; Mohammad Kamalinejad; Nepton Soltani; Nima Pouladian
Journal:  Pharmacognosy Res       Date:  2017 Oct-Dec

7.  Bioactive glycoalkaloides isolated from Solanum melongena fruit peels with potential anticancer properties against hepatocellular carcinoma cells.

Authors:  Mostafa I Fekry; Shahira M Ezzat; Maha M Salama; Ohoud Y Alshehri; Ahmed M Al-Abd
Journal:  Sci Rep       Date:  2019-02-11       Impact factor: 4.379

8.  Regeneration of Solanum nigrum by somatic embryogenesis, involving frog egg-like body, a novel structure.

Authors:  Kedong Xu; Yunxia Chang; Kun Liu; Feige Wang; Zhongyuan Liu; Ting Zhang; Tong Li; Yi Zhang; Fuli Zhang; Ju Zhang; Yan Wang; Wei Niu; Shuzhao Jia; Hengchang Xie; Guangxuan Tan; Chengwei Li
Journal:  PLoS One       Date:  2014-06-04       Impact factor: 3.240

9.  Solanum nigrum Unripe fruit fraction attenuates Adriamycin resistance by down-regulating multi-drug resistance protein (Mdr)-1 through Jak-STAT pathway.

Authors:  Sankar Jagadeeshan; Diana David; S Jisha; S Manjula; S Asha Nair
Journal:  BMC Complement Altern Med       Date:  2017-07-18       Impact factor: 3.659

10.  Histomorphology, Sperm Quality and Hormonal Profile in Adult Male Sprague-Dawley Rats following administration of aqueous crude Extract of Solanum nigrum by gastric gavage.

Authors:  Sunday Aderemi Adelakun; Babatunde Ogunlade; Toluwase Solomon Olawuyi; Julius Akomaye Aniah; Olusegun Dare Omotoso
Journal:  JBRA Assist Reprod       Date:  2018-11-01
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