Literature DB >> 11429118

Characterization and phylogenetic analysis of South African HIV-1 subtype C accessory genes.

T J Scriba1, F K Treurnicht, M Zeier, S Engelbrecht, E J van Rensburg.   

Abstract

To acquire new knowledge about the genetic diversity and potential impact on vaccine strategies of HIV-1 subtype C in South Africa, we have characterized the vif, vpr, and vpu genes of 15 isolates. Phylogenetic analysis of the genomic fragment encompassing these genes revealed subtype C subclusters, suggesting close relatedness with subtype C strains from other geographic locations and excluded isolation of South African strains. The putative T155 phosphorylation site in the C terminal of Vif was absent in all subtype C sequences. Variation in the predicted amino acid sequences of the three genes further showed strong correlation with other subtype C sequences.

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Year:  2001        PMID： 11429118     DOI： 10.1089/088922201750237059

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  9 in total

1.  Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates.

Authors:  Gillian M Hunt; Maria A Papathanasopoulos; Glenda E Gray; Caroline T Tiemessen
Journal:  Virus Genes       Date:  2003-01       Impact factor: 2.332

2.  Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.

Authors:  Raabya Rossenkhan; Iain J MacLeod; Zabrina L Brumme; Craig A Magaret; Theresa K Sebunya; Rosemary Musonda; Berhanu A Gashe; Paul T Edlefsen; Vlad Novitsky; M Essex
Journal:  AIDS Res Hum Retroviruses       Date:  2016-07-26       Impact factor: 2.205

3.  Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes.

Authors:  Kavidha Reddy; Marcel Ooms; Michael Letko; Nigel Garrett; Viviana Simon; Thumbi Ndung'u
Journal:  AIDS       Date:  2016-07-17       Impact factor: 4.177

4.  Identification of subtype C human immunodeficiency virus type 1 by subtype-specific PCR and its use in the characterization of viruses circulating in the southern parts of India.

Authors:  Nagadenahalli B Siddappa; Prashanta K Dash; Anita Mahadevan; Narayana Jayasuryan; Fen Hu; Bethany Dice; Randy Keefe; Kadappa S Satish; Bhuthiah Satish; Kuttan Sreekanthan; Ramdas Chatterjee; Kandala Venu; Parthasarathy Satishchandra; Vasanthapuram Ravi; Susarla K Shankar; Raj Shankarappa; Udaykumar Ranga
Journal:  J Clin Microbiol       Date:  2004-06       Impact factor: 5.948

5.  Genetic characterization of natural variants of Vpu from HIV-1 infected individuals from Northern India and their impact on virus release and cell death.

Authors:  Sachin Verma; Larance Ronsard; Richa Kapoor; Akhil C Banerjea
Journal:  PLoS One       Date:  2013-03-28       Impact factor: 3.240

6.  Multiple NF-κB sites in HIV-1 subtype C long terminal repeat confer superior magnitude of transcription and thereby the enhanced viral predominance.

Authors:  Mahesh Bachu; Swarupa Yalla; Mangaiarkarasi Asokan; Anjali Verma; Ujjwal Neogi; Shilpee Sharma; Rajesh V Murali; Anil Babu Mukthey; Raghavendra Bhatt; Snehajyoti Chatterjee; Roshan Elizabeth Rajan; Narayana Cheedarla; Venkat S Yadavalli; Anita Mahadevan; Susarla K Shankar; Nirmala Rajagopalan; Anita Shet; Shanmugam Saravanan; Pachamuthu Balakrishnan; Suniti Solomon; Madhu Vajpayee; Kadappa Shivappa Satish; Tapas K Kundu; Kuan-Teh Jeang; Udaykumar Ranga
Journal:  J Biol Chem       Date:  2012-11-06       Impact factor: 5.157

7.  Viral diversity and diversification of major non-structural genes vif, vpr, vpu, tat exon 1 and rev exon 1 during primary HIV-1 subtype C infection.

Authors:  Raabya Rossenkhan; Vladimir Novitsky; Theresa K Sebunya; Rosemary Musonda; Berhanu A Gashe; M Essex
Journal:  PLoS One       Date:  2012-05-09       Impact factor: 3.240

8.  Evolutional insights on uncharacterized SARS coronavirus genes.

Authors:  Alex Inberg; Michal Linial
Journal:  FEBS Lett       Date:  2004-11-05       Impact factor: 4.124

9.  Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection.

Authors:  Prasanta K Dash; Nagadenahalli B Siddappa; Asokan Mangaiarkarasi; Aruna V Mahendarkar; Padmanabhan Roshan; Krishnamurthy Kumar Anand; Anita Mahadevan; Parthasarathy Satishchandra; Susarla K Shankar; Vinayaka R Prasad; Udaykumar Ranga
Journal:  Retrovirology       Date:  2008-03-07       Impact factor: 4.602
  9 in total

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