Literature DB >> 11427043

Rational approaches to the design of cationic gemini surfactants for gene delivery.

C McGregor1, C Perrin, M Monck, P Camilleri, A J Kirby.   

Abstract

We report a new class of amphiphilic gemini surfactants as vehicles for gene delivery into cells, and the beginnings of a systematic structure-activity study. Preliminary results suggest that combining gemini surfactants with dioleoylphosphatidylethanolamine (DOPE) should allow the preparation of liposomes of various sizes and lipid compositions. Control of such colloidal changes could be as significant as the changes in the molecular composition of the gemini surfactants in delivering optimum gene expression in animal models.

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Year:  2001        PMID： 11427043     DOI： 10.1021/ja005681c

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  11 in total

Review 1.  Transfection by cationic gemini lipids and surfactants.

Authors:  M Damen; A J J Groenen; S F M van Dongen; R J M Nolte; B J Scholte; M C Feiters
Journal:  Medchemcomm       Date:  2018-07-17       Impact factor: 3.597

2.  Novel gemini cationic lipids with carbamate groups for gene delivery.

Authors:  Yi-Nan Zhao; Farooq Qureshi; Shu-Biao Zhang; Shao-Hui Cui; Bing Wang; Hui-Ying Chen; Hong-Tao Lv; Shu-Fen Zhang; Leaf Huang
Journal:  J Mater Chem B       Date:  2014-05-21       Impact factor: 6.331

Review 3.  Lipid and polymeric carrier-mediated nucleic acid delivery.

Authors:  Lin Zhu; Ram I Mahato
Journal:  Expert Opin Drug Deliv       Date:  2010-10       Impact factor: 6.648

4.  Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery.

Authors:  Xiao-Xiang Zhang; Carla A H Prata; Jason A Berlin; Thomas J McIntosh; Philippe Barthelemy; Mark W Grinstaff
Journal:  Bioconjug Chem       Date:  2011-04-01       Impact factor: 4.774

Review 5.  A review on progress in QSPR studies for surfactants.

Authors:  Jiwei Hu; Xiaoyi Zhang; Zhengwu Wang
Journal:  Int J Mol Sci       Date:  2010-03-08       Impact factor: 6.208

6.  Bioreducible liposomes for gene delivery: from the formulation to the mechanism of action.

Authors:  Gabriele Candiani; Daniele Pezzoli; Laura Ciani; Roberto Chiesa; Sandra Ristori
Journal:  PLoS One       Date:  2010-10-15       Impact factor: 3.240

7.  Very long chain N4, N9 -diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery.

Authors:  Hassan M Ghonaim; Shi Li; Ian S Blagbrough
Journal:  Pharm Res       Date:  2008-09-10       Impact factor: 4.200

8.  Steric inhibition of human immunodeficiency virus type-1 Tat-dependent trans-activation in vitro and in cells by oligonucleotides containing 2'-O-methyl G-clamp ribonucleoside analogues.

Authors:  Stephen C Holmes; Andrey A Arzumanov; Michael J Gait
Journal:  Nucleic Acids Res       Date:  2003-06-01       Impact factor: 16.971

9.  New-Generation Benzimidazole-Based Plasmid Delivery Reagents with High Transfection Efficiencies on the Mammalian Cells.

Authors:  Furkan Ayaz; Ronak Haj Ersan; Burak Kuzu; Oztekin Algul
Journal:  In Vitro Cell Dev Biol Anim       Date:  2020-01-02       Impact factor: 2.416

10.  Peptide dendrimer/lipid hybrid systems are efficient DNA transfection reagents: structure--activity relationships highlight the role of charge distribution across dendrimer generations.

Authors:  Albert Kwok; Gabriela A Eggimann; Jean-Louis Reymond; Tamis Darbre; Florian Hollfelder
Journal:  ACS Nano       Date:  2013-05-17       Impact factor: 15.881
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