Literature DB >> 11425526

Quinoline-4-acetamides as sPLA(2) inhibitors.

Y Liu1, Y Feng, R Wang, Y Gao, L Lai.   

Abstract

Quinoline-4-acetamides were designed as potential phospholipase A(2) inhibitors by structural based method and synthesized. The chemical structures of the obtained compounds were confirmed by elemental analyses, 1H NMR and MS. Preliminary bioassay study shows that quinoline-4-acetamides display certain inhibition to sPLA(2).

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Year:  2001        PMID: 11425526     DOI: 10.1016/s0960-894x(01)00229-3

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Utility of alkylaminoquinolinyl methanols as new antimalarial drugs.

Authors:  G S Dow; T N Heady; A K Bhattacharjee; D Caridha; L Gerena; M Gettayacamin; C A Lanteri; N Obaldia; N Roncal; T Shearer; P L Smith; A Tungtaeng; L Wolf; M Cabezas; D Yourick; K S Smith
Journal:  Antimicrob Agents Chemother       Date:  2006-09-11       Impact factor: 5.191

  1 in total

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