Literature DB >> 11425522

Enantioselective synthesis and complement inhibitory assay of A/B-ring partial analogues of oleanolic acid.

H Assefa1, A Nimrod, L Walker, R Sindelar.   

Abstract

A series of oleanolic acid A/B-ring partial analogues was synthesized and tested for their complement inhibitory activity as well as cytotoxic properties. All target compounds and one intermediate exhibited moderate complement inhibitory potency. These compounds also showed cytotoxicity on malignant melanoma cell line, SK-MEL.

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Year:  2001        PMID： 11425522     DOI： 10.1016/s0960-894x(01)00210-4

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  Effects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15.

Authors:  Jie Li; Wei-Jian Guo; Qing-Yao Yang
Journal:  World J Gastroenterol       Date:  2002-06       Impact factor: 5.742

Review 2.  Recent developments in low molecular weight complement inhibitors.

Authors:  Hongchang Qu; Daniel Ricklin; John D Lambris
Journal:  Mol Immunol       Date:  2009-10-02       Impact factor: 4.407

3.  Unexpected Racemization in the Course of the Acetalization of (+)-(S)-5-Methyl-Wieland-Miescher Ketone with 1,2-Ethanediol and TsOH under Classical Experimental Conditions.

Authors:  Francesca Leonelli; Irene Piergentili; Giulio Lucarelli; Luisa Maria Migneco; Rinaldo Marini Bettolo
Journal:  Int J Mol Sci       Date:  2019-12-05       Impact factor: 5.923

4.  Fruits of Vitex doniana sweet: toxicity profile, anti-inflammatory and antioxidant activities, and quantification of one of its bioactive constituents oleanolic acid.

Authors:  Silas Adjei; Isaac Kingsley Amponsah; Samuel Oppong Bekoe; Benjamin Kingsley Harley; Kwesi Boadu Mensah; Abraham Yeboah Mensah; Michael Kwesi Baah; Gabriel Fosu-Mensah
Journal:  Heliyon       Date:  2021-09-02

5.  Mechanical property and structure of covalent functionalised graphene/epoxy nanocomposites.

Authors:  Minoo Naebe; Jing Wang; Abbas Amini; Hamid Khayyam; Nishar Hameed; Lu Hua Li; Ying Chen; Bronwyn Fox
Journal:  Sci Rep       Date:  2014-03-14       Impact factor: 4.379

6.  Facile synthesis of α-alkoxymethyltriphenylphosphonium iodides: new application of PPh3/I2.

Authors:  Humaira Yasmeen Gondal; Zain Maqsood Cheema; Javid Hussain Zaidi; Sammer Yousuf; M Iqbal Choudhary
Journal:  Chem Cent J       Date:  2018-05-17       Impact factor: 4.215
  6 in total

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