OBJECTIVE: To assess the effects of the ingestion of milk, yoghurt (10(8) bacteria/ml), heat-treated yoghurt (<15 bacteria/ml) and two products obtained by dilution of yoghurt with heat-treated product (10(6) and 10(5) bacteria/ml) on hydrogen production and symptoms of lactose intolerance in lactose malabsorbers. DESIGN: Double-blind, randomised cross-over design. SETTING: The study was performed in the phase 1 clinical unit of OPTIMED, Nancy, France. SUBJECTS:Twenty-four male lactose malabsorbers were selected for the study. INTERVENTIONS:Hydrogen production and adverse events were followed during 8 h after ingestion of the products. RESULTS: The results clearly demonstrate that ingestion of yoghurt with 10(8) bacteria/ml leads to lower H(2) excretion and complaints than the other products. Results observed with the products containing a reduced population of live flora remain better than those observed with milk. CONCLUSIONS: The importance of a high population of the live flora is underlined.
RCT Entities:
OBJECTIVE: To assess the effects of the ingestion of milk, yoghurt (10(8) bacteria/ml), heat-treated yoghurt (<15 bacteria/ml) and two products obtained by dilution of yoghurt with heat-treated product (10(6) and 10(5) bacteria/ml) on hydrogen production and symptoms of lactose intolerance in lactose malabsorbers. DESIGN: Double-blind, randomised cross-over design. SETTING: The study was performed in the phase 1 clinical unit of OPTIMED, Nancy, France. SUBJECTS: Twenty-four male lactose malabsorbers were selected for the study. INTERVENTIONS:Hydrogen production and adverse events were followed during 8 h after ingestion of the products. RESULTS: The results clearly demonstrate that ingestion of yoghurt with 10(8) bacteria/ml leads to lower H(2) excretion and complaints than the other products. Results observed with the products containing a reduced population of live flora remain better than those observed with milk. CONCLUSIONS: The importance of a high population of the live flora is underlined.
Authors: Mohammad Aghajanpour; Mohamad Reza Nazer; Zia Obeidavi; Mohsen Akbari; Parya Ezati; Nasroallah Moradi Kor Journal: Am J Cancer Res Date: 2017-04-01 Impact factor: 6.166
Authors: Olga Maria Nardone; Francesco Manfellotto; Caterina D'Onofrio; Alba Rocco; Giovanni Annona; Francesca Sasso; Pasquale De Luca; Nicola Imperatore; Anna Testa; Roberto de Sire; Elio Biffali; Fabiana Castiglione Journal: Nutrients Date: 2021-04-14 Impact factor: 5.717