BACKGROUND: The International Study of Asthma and Allergies in Childhood (ISAAC) was designed to allow international comparison of epidemiological data on atopic conditions in childhood. In so doing, further aetiological information would be obtained that in turn would provide a framework for future studies. The global ISAAC results on the prevalence of atopic dermatitis indicated a 60-fold variation recorded in different countries. Such a degree of difference may be partially due to the translated questionnaires that were not validated in all of the involved countries. OBJECTIVE: To validate the Chinese version of the ISAAC core questions for atopic eczema. METHODS: One thousand nine hundred and twenty children aged between 3 and 5 were randomly recruited from 13 kindergartens in Hong Kong. Using a dermatologist's clinical examination as the gold standard, we validated the Chinese version of the ISAAC core questions for atopic eczema. The Youden's Indexes obtained in our study were compared with those obtained in the United Kingdom's validation study. RESULTS: The Youden's Indexes obtained in our study were significantly lower than those from the United Kingdom. The low scores were likely to be due to a reduction in the sensitivity of the Chinese questionnaire, which ranged from 23.5% to 70.6%. CONCLUSION: Our findings indicate that the translated questionnaire is less effective than the English version in assessing the prevalence of atopic eczema. The indication of a low prevalence of atopic eczema among the Chinese population reported in previous studies was at least partially due to problems with the translated questionnaire.
BACKGROUND: The International Study of Asthma and Allergies in Childhood (ISAAC) was designed to allow international comparison of epidemiological data on atopic conditions in childhood. In so doing, further aetiological information would be obtained that in turn would provide a framework for future studies. The global ISAAC results on the prevalence of atopic dermatitis indicated a 60-fold variation recorded in different countries. Such a degree of difference may be partially due to the translated questionnaires that were not validated in all of the involved countries. OBJECTIVE: To validate the Chinese version of the ISAAC core questions for atopic eczema. METHODS: One thousand nine hundred and twenty children aged between 3 and 5 were randomly recruited from 13 kindergartens in Hong Kong. Using a dermatologist's clinical examination as the gold standard, we validated the Chinese version of the ISAAC core questions for atopic eczema. The Youden's Indexes obtained in our study were compared with those obtained in the United Kingdom's validation study. RESULTS: The Youden's Indexes obtained in our study were significantly lower than those from the United Kingdom. The low scores were likely to be due to a reduction in the sensitivity of the Chinese questionnaire, which ranged from 23.5% to 70.6%. CONCLUSION: Our findings indicate that the translated questionnaire is less effective than the English version in assessing the prevalence of atopic eczema. The indication of a low prevalence of atopic eczema among the Chinese population reported in previous studies was at least partially due to problems with the translated questionnaire.
Authors: Agostino Strina; Mauricio L Barreto; Sergio Cunha; Maria de Fátima S P de Oliveira; Shirlei C Moreira; Hywel C Williams; Laura C Rodrigues Journal: BMC Dermatol Date: 2010-11-09
Authors: Tina V Hartert; Xinqing Deng; Terryl J Hartman; Wanqing Wen; Gong Yang; Yu-Tang Gao; Meiling Jin; Chunxue Bai; Myron Gross; L Jackson Roberts; James R Sheller; John Christman; William Dupont; Marie Griffin; Xiao Ou Shu Journal: Am J Epidemiol Date: 2008-04-07 Impact factor: 4.897
Authors: Qian Chen; Rong Huang; Li Hua; Yifeng Guo; Lisu Huang; Yanjun Zhao; Xia Wang; Jun Zhang Journal: Environ Health Date: 2018-01-17 Impact factor: 5.984