| Literature DB >> 11421746 |
S M Costa1, T L Lemos, O D Pessoa, C Pessoa, R C Montenegro, R Braz-Filho.
Abstract
Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone (13), were isolated from ethanol extracts of Lippia sidoides. Their structures were established by a combination of 1D and 2D NMR, IR, and EIMS spectral data analysis. The cytotoxic properties of compounds 3--13 were evaluated against HL60, SW1573, and CEM cell lines. Only tectol (6) and lippsidoquinone (13) exhibited significant activity against human leukemia cell lines HL60 and CEM.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11421746 DOI: 10.1021/np0005917
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050