Literature DB >> 11421733

Two new cytotoxic and virucidal trisulfated triterpene glycosides from the Antarctic sea cucumber Staurocucumis liouvillei.

M S Maier1, A J Roccatagliata, A Kuriss, H Chludil, A M Seldes, C A Pujol, E B Damonte.   

Abstract

Two new trisulfated triterpene glycosides, liouvillosides A (1) and B (2), have been isolated from the Antarctic sea cucumber Staurocucumis liouvillei. Their structures have been elucidated by spectroscopic analysis (NMR and FABMS) and chemical transformations. Liouvillosides A (1) and B (2) are two new examples of a small number of trisulfated triterpene glycosides from sea cucumbers belonging to the family Cucumariidae. Both glycosides were found to be virucidal against herpes simplex virus type 1 (HSV-1) at concentrations below 10 microg/mL.

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Year:  2001        PMID: 11421733     DOI: 10.1021/np000584i

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  15 in total

1.  Two novel glucosylceramides from gonads and body walls of the Patagonian starfish Allostichaster inaequalis.

Authors:  María E Díaz de Vivar; Alicia M Seldes; Marta S Maier
Journal:  Lipids       Date:  2002-06       Impact factor: 1.880

2.  Patagonicosides B and C, two antifungal sulfated triterpene glycosides from the sea cucumber Psolus patagonicus.

Authors:  Valeria P Careaga; Claudia Muniain; Marta S Maier
Journal:  Chem Biodivers       Date:  2011-03       Impact factor: 2.408

Review 3.  High-value components and bioactives from sea cucumbers for functional foods--a review.

Authors:  Sara Bordbar; Farooq Anwar; Nazamid Saari
Journal:  Mar Drugs       Date:  2011-10-10       Impact factor: 6.085

4.  Structure elucidation of five novel isomeric saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Tim Chataway; Chris Franco
Journal:  Mar Drugs       Date:  2014-08-08       Impact factor: 5.118

5.  Cytotoxic and apoptosis-inducing activity of triterpene glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 cells.

Authors:  Juanjuan Wang; Hua Han; Xiangfeng Chen; Yanghua Yi; Hongxiang Sun
Journal:  Mar Drugs       Date:  2014-07-24       Impact factor: 5.118

Review 6.  Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties.

Authors:  Muhammad Abdul Mojid Mondol; Hee Jae Shin; M Aminur Rahman; Mohamad Tofazzal Islam
Journal:  Mar Drugs       Date:  2017-10-17       Impact factor: 5.118

7.  Discovery of novel saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Chris Franco
Journal:  Mar Drugs       Date:  2014-05-09       Impact factor: 5.118

8.  Variegatusides: new non-sulphated triterpene glycosides from the sea cucumber Stichopus variegates semper.

Authors:  Xiao-Hua Wang; Zheng-Rong Zou; Yang-Hua Yi; Hua Han; Ling Li; Min-Xiang Pan
Journal:  Mar Drugs       Date:  2014-04-02       Impact factor: 5.118

Review 9.  Acetylated Triterpene Glycosides and Their Biological Activity from Holothuroidea Reported in the Past Six Decades.

Authors:  Yadollah Bahrami; Christopher M M Franco
Journal:  Mar Drugs       Date:  2016-08-04       Impact factor: 5.118

10.  Anti-Skin Cancer Activities of Apostichopus japonicus Extracts from Low-Temperature Ultrasonification Process.

Authors:  Nam Young Kim; Woon Yong Choi; Soo Jin Heo; Do Hyung Kang; Hyeon Yong Lee
Journal:  J Healthc Eng       Date:  2017-05-15       Impact factor: 2.682

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