Literature DB >> 11421725

A new dehydrogeranylgeraniol antioxidant from Saururus cernuus that inhibits intracellular reactive oxygen species (ROS)-catalyzed oxidation within HL-60 cells.

I Rajbhandari1, S Takamatsu, D G Nagle.   

Abstract

A new triene, 12,13-dehydrogeranylgeraniol (1), was isolated from the aquatic plant Saururus cernuus and its structure determined spectroscopically. Compound 1 inhibits PMA-induced peroxide-catalyzed oxidation of 2',7'-dichlorodihydrofluorescein dye (DCFH) by reactive oxygen species (ROS) within human promyelocyctic HL-60 cells.

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Year:  2001        PMID： 11421725     DOI： 10.1021/np0101346

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

1.  Mercury concentrations in oligohaline wetland vegetation and associated soil biogeochemistry.

Authors:  Jonathan M Willis; Robert P Gambrell; Mark W Hester
Journal:  Environ Monit Assess       Date:  2010-12-29       Impact factor: 2.513

Review 2.  Isoprenoids: remarkable diversity of form and function.

Authors:  Sarah A Holstein; Raymond J Hohl
Journal:  Lipids       Date:  2004-04       Impact factor: 1.880

3.  Marine natural products as novel antioxidant prototypes.

Authors:  Satoshi Takamatsu; Tyler W Hodges; Ira Rajbhandari; William H Gerwick; Mark T Hamann; Dale G Nagle
Journal:  J Nat Prod       Date:  2003-05       Impact factor: 4.050
  3 in total

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