Effect of exercise on lipid metabolism of rats fed high carbohydrate diets.

Two experiments were conducted to determine whether high carbohydrate diets or exercise would have a greater influence on certain parameters of lipid metabolism. Male Fischer rats were used in both experiments, separated into exercise and sedentary groups, and fed either a high sucrose (63%) or a high starch (63%) diet. There were no differences in body weight or food consumption between the two diets. Exercise resulted in a highly significant increase in food consumption in both experiments. Rats fed sucrose had a higher serum cholesterol value than rats fed starch. Diet did not influence serum triglycerides but the rats on excercise had significantly lower serum triglycerides than the sedentary rats. Liver weight was significantly larger in rats fed sucrose. Sucrose caused an increase in the activity of both glucose-6-phosphate dehydrogenase and malic enzyme activities in liver tissue, whereas exercise caused an increase in the activity of these enzymes in adipose tissue.