Literature DB >> 11419915

Gastro-Oesophageal reflux in the elderly: role of drug therapy in management.

A B Thomson1.   

Abstract

Gastro-oesophageal reflux disease (GORD) is common in the elderly. The presenting symptoms of heartburn and regurgitation, so common in the young, are less frequent in the elderly. Common symptoms of GORD in the elderly are dysphagia, vomiting and respiratory problems. Because of the higher risk of associated pathological oesophageal lesions in the older person presenting with symptoms suggestive of GORD, oesophagogastroduodenoscopy must be performed earlier in their clinical course. There is only a poor correlation between the severity of the symptoms and the severity of the associated oesophagitis. Whereas lifestyle modifications are important in individuals with GORD, the use of proton pump inhibitors is recommended to heal the underlying pathology, to resolve the patient's symptoms, to prevent complications, and to improve the quality of life.

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Year:  2001        PMID: 11419915     DOI: 10.2165/00002512-200118060-00003

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  61 in total

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Journal:  Dysphagia       Date:  1997       Impact factor: 3.438

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Journal:  Gerontology       Date:  1993       Impact factor: 5.140

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Journal:  Dig Dis Sci       Date:  1994-10       Impact factor: 3.199

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Journal:  Dtsch Med Wochenschr       Date:  1993-10-29       Impact factor: 0.628

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Journal:  Am J Gastroenterol       Date:  1991-08       Impact factor: 10.864

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Journal:  Postgrad Med J       Date:  1995-02       Impact factor: 2.401

Review 9.  Review article: a role for gastrointestinal prokinetic agents in the treatment of reflux oesophagitis?

Authors:  M Verlinden
Journal:  Aliment Pharmacol Ther       Date:  1989-04       Impact factor: 8.171

10.  A comparison of five maintenance therapies for reflux esophagitis.

Authors:  S Vigneri; R Termini; G Leandro; S Badalamenti; M Pantalena; V Savarino; F Di Mario; G Battaglia; G S Mela; A Pilotto
Journal:  N Engl J Med       Date:  1995-10-26       Impact factor: 91.245

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  3 in total

1.  Influence of age on outcome of total laparoscopic fundoplication for gastroesophageal reflux disease.

Authors:  F Pizza; G Rossetti; P Limongelli; G Del Genio; V Maffettone; V Napolitano; L Brusciano; G Russo; S Tolone; M Di Martino; A Del Genio
Journal:  World J Gastroenterol       Date:  2007-02-07       Impact factor: 5.742

Review 2.  Medical management of nocturnal symptoms of gastro-oesophageal reflux disease in the elderly.

Authors:  Samer Gawrieh; Reza Shaker
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

Review 3.  Treatment of acid-related diseases in the elderly with emphasis on the use of proton pump inhibitors.

Authors:  Bjarni Thjodleifsson
Journal:  Drugs Aging       Date:  2002       Impact factor: 3.923

  3 in total

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