Literature DB >> 11418582

Multiple genes for the last step of proline biosynthesis in Bacillus subtilis.

B R Belitsky1, J Brill, E Bremer, A L Sonenshein.   

Abstract

The complete Bacillus subtilis genome contains four genes (proG, proH, proI, and comER) with the potential to encode Delta(1)-pyrroline-5-carboxylate reductase, a proline biosynthetic enzyme. Simultaneous defects in three of these genes (proG, proH, and proI) were required to confer proline auxotrophy, indicating that the products of these genes are mostly interchangeable with respect to the last step in proline biosynthesis.

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Year:  2001        PMID： 11418582      PMCID： PMC95331          DOI： 10.1128/JB.183.14.4389-4392.2001

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  30 in total

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