| Literature DB >> 11418059 |
T Harada1, H Iwai, H Takatsuki, K Fujita, M Kubo, A Oku.
Abstract
[reaction: see text] O-(2-Naphthoyl)-N-tosyl-L-allo-threonine-derived B-phenyloxazaborolidinone catalyzes the asymmetric Mukaiyama-Michael addition of simple acyclic enones to give adducts of 54-85% ee. 2,6-Diisopropylphenol as an additive is demonstrated to effectively retard the undesirable Si(+)-catalyzed racemic pathway.Entities:
Year: 2001 PMID： 11418059 DOI： 10.1021/ol016062r
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005