Literature DB >> 11413904

Pharmacologic treatment of the adult hospitalized asthma patient.

M L Kreutzer1, S Louie.   

Abstract

Acute severe asthma calls for aggressive and early therapy of a multifaceted and all-inclusive approach (Fig. 2). Therapy merely begins in the ED and manifold distinct issues need to find consideration during ongoing hospital care. Currently, beta-agonists, anti-cholinergic agents, and corticosteroids remain the mainstay of therapy. Methylxanthines and magnesium may find consideration in carefully selected patients. Multiple new therapeutic avenues, such as the anti-leukotriene drugs, seem promising and future studies will hopefully extend our armamentarium against life threatening complication of a common disease. Asthma education begun in the hospital may provide the platform for preventing severe acute exacerbations and hospitalization.

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Year:  2001        PMID: 11413904     DOI: 10.1385/CRIAI:20:3:357

Source DB:  PubMed          Journal:  Clin Rev Allergy Immunol        ISSN: 1080-0549            Impact factor:   8.667


  111 in total

1.  Tolerance to beta-agonists during acute bronchoconstriction.

Authors:  R J Hancox; R E Aldridge; J O Cowan; E M Flannery; G P Herbison; C R McLachlan; G I Town; D R Taylor
Journal:  Eur Respir J       Date:  1999-08       Impact factor: 16.671

2.  Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma.

Authors:  B J O'Connor; S L Aikman; P J Barnes
Journal:  N Engl J Med       Date:  1992-10-22       Impact factor: 91.245

3.  Can MDIs be used effectively by extubated ICU patients?

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Journal:  J Crit Illn       Date:  1992-01

Review 4.  Molecular mechanisms of beta-adrenergic relaxation of airway smooth muscle.

Authors:  M I Kotlikoff; K E Kamm
Journal:  Annu Rev Physiol       Date:  1996       Impact factor: 19.318

5.  Inhaled glucocorticoids and acute asthma: therapeutic breakthrough or nonspecific effect?

Authors:  E R McFadden
Journal:  Am J Respir Crit Care Med       Date:  1998-03       Impact factor: 21.405

6.  The role of ipratropium bromide in the emergency management of acute asthma exacerbation: a metaanalysis of randomized clinical trials.

Authors:  R G Stoodley; S D Aaron; R E Dales
Journal:  Ann Emerg Med       Date:  1999-07       Impact factor: 5.721

7.  Improved bronchodilation with levalbuterol compared with racemic albuterol in patients with asthma.

Authors:  H S Nelson; G Bensch; W W Pleskow; R DiSantostefano; S DeGraw; D S Reasner; T E Rollins; P D Rubin
Journal:  J Allergy Clin Immunol       Date:  1998-12       Impact factor: 10.793

8.  Ventilation-perfusion mismatching in acute severe asthma: effects of salbutamol and 100% oxygen.

Authors:  E Ballester; A Reyes; J Roca; R Guitart; P D Wagner; R Rodriguez-Roisin
Journal:  Thorax       Date:  1989-04       Impact factor: 9.139

9.  Cardiovascular safety of high doses of inhaled fenoterol and albuterol in acute severe asthma.

Authors:  M T Newhouse; K R Chapman; A L McCallum; R T Abboud; D M Bowie; R V Hodder; P D Paré; H Mesic-Fuchs; N A Molfino
Journal:  Chest       Date:  1996-09       Impact factor: 9.410

Review 10.  Steroid resistance in asthma.

Authors:  P J Barnes; I M Adcock
Journal:  QJM       Date:  1995-07
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  2 in total

Review 1.  Inhaled magnesium sulfate in the treatment of acute asthma.

Authors:  Rachel Knightly; Stephen J Milan; Rodney Hughes; Jennifer A Knopp-Sihota; Brian H Rowe; Rebecca Normansell; Colin Powell
Journal:  Cochrane Database Syst Rev       Date:  2017-11-28

Review 2.  Severe asthma.

Authors:  Nicholas J Kenyon; Nizar N Jarjour
Journal:  Clin Rev Allergy Immunol       Date:  2003-10       Impact factor: 8.667

  2 in total

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