| Literature DB >> 11413373 |
Laurens Kils-Hütten1, Rémi Cheynier2, Simon Wain-Hobson2, Andreas Meyerhans1.
Abstract
The intra-host evolution of 73 human immunodeficiency virus type 1 quasispecies was analysed by split decomposition analysis. Non-synonymous and synonymous nucleotide substitutions were counted along the shortest path connecting all sequences and compared with the numbers expected under the assumption of a random model of mutation. For the majority of substitutions, drift and negative selection seemed to prevail.Entities:
Mesh:
Year: 2001 PMID: 11413373 DOI: 10.1099/0022-1317-82-7-1621
Source DB: PubMed Journal: J Gen Virol ISSN: 0022-1317 Impact factor: 3.891