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Literature DB >> 11412969

Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display.

J W Chin¹, R M Grotzfeld, M A Fabian, A Schepartz.

Abstract

Synthetic genes for avian pancreatic polypeptide (aPP) and for the miniature DNA binding protein PPBR4 were cloned and expressed on the surface of M13 bacteriophage. We anticipate that these constructs will have utility optimizing the properties of miniature proteins based on aPP that result from our previously described protein grafting procedure.

Entities: Disease Gene Species

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Year: 2001 PMID： 11412969 DOI： 10.1016/s0960-894x(01)00139-1

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

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Cited

11 in total

1. Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain.

Authors: Stacey E Rutledge; Heather M Volkman; Alanna Schepartz
Journal: J Am Chem Soc Date: 2003-11-26 Impact factor: 15.419

2. beta-Peptides as inhibitors of protein-protein interactions.

Authors: Joshua A Kritzer; Olen M Stephens; Danielle A Guarracino; Samuel K Reznik; Alanna Schepartz
Journal: Bioorg Med Chem Date: 2005-01-03 Impact factor: 3.641

3. Correlation between imaging features of Pneumocystis Jiroveci Pneumonitis (PCP), CD(4) (+) T lymphocyte count, and plasma HIV viral load: A study in 50 consecutive AIDS patients.

Authors: Pu-Xuan Lu; Ying-Ying Deng; Shui-Teng Liu; Yan Liu; Ying-Xia Liu; Yi-Xiang J Wang; Wen-Ke Zhu; Xiao-Hua Le; Wei-Ye Yu; Bo-Ping Zhou
Journal: Quant Imaging Med Surg Date: 2012-06

4. Effective molarity redux: Proximity as a guiding force in chemistry and biology.

Authors: Elissa M Hobert; Amy E Doerner; Allison S Walker; Alanna Schepartz
Journal: Isr J Chem Date: 2013-08 Impact factor: 3.333

5. Reprogramming the genetic code.

Authors: Jason W Chin
Journal: EMBO J Date: 2011-05-20 Impact factor: 11.598

6. Exploring new strategies for grafting binding peptides onto protein loops using a consensus-designed tetratricopeptide repeat scaffold.

Authors: Sarah K Madden; Albert Perez-Riba; Laura S Itzhaki
Journal: Protein Sci Date: 2019-04 Impact factor: 6.993

Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display.

1. Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain.

2. beta-Peptides as inhibitors of protein-protein interactions.

3. Correlation between imaging features of Pneumocystis Jiroveci Pneumonitis (PCP), CD(4) (+) T lymphocyte count, and plasma HIV viral load: A study in 50 consecutive AIDS patients.

4. Effective molarity redux: Proximity as a guiding force in chemistry and biology.

5. Reprogramming the genetic code.

6. Exploring new strategies for grafting binding peptides onto protein loops using a consensus-designed tetratricopeptide repeat scaffold.

7. Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface.

8. Robust production of a peptide library using methodological synchronization.

9. Minimalist proteins: Design of new molecular recognition scaffolds.

Review 10. Constrained peptides as miniature protein structures.