Literature DB >> 11412853

Oxidative stress, aging and longevity in Drosophila melanogaster.

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Abstract

Free radicals produced during normal metabolism cause damage to macromolecules. The free radical theory of aging proposes that the organism is unable to repair all of them and that, with time, unrepaired damages accumulate and put the organism at risk: in other words, free radicals provoke aging and death. This article reviews both the results of adding antioxidants to food on longevity in Drosophila melanogaster, as well as the studies on antioxidant enzymes (inactivation in vivo, null mutants, overexpression). It is concluded that antioxidant enzymes are probably poorly connected to the normal aging process, but they allow the organism to cope with stressful conditions.

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Year:  2001        PMID： 11412853     DOI： 10.1016/s0014-5793(01)02457-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  11 in total

1.  Sex differences in oxidative stress resistance in relation to longevity in Drosophila melanogaster.

Authors:  S Niveditha; S Deepashree; S R Ramesh; T Shivanandappa
Journal:  J Comp Physiol B       Date:  2017-03-06       Impact factor: 2.200

2.  Genetic repression of the antioxidant enzymes reduces the lifespan in Drosophila melanogaster.

Authors:  S Deepashree; T Shivanandappa; Saraf R Ramesh
Journal:  J Comp Physiol B       Date:  2021-10-08       Impact factor: 2.200

3.  Pharmacological Effect of Caffeine on Drosophila melanogaster: A Proof-of-Concept in vivo Study for Nootropic Investigation.

Authors:  A Asbah; U Ummussaadah; N Parenden; A S W Putri; R A Rosa; N R Rumata; T B Emran; K Dhama; F Nainu
Journal:  Arch Razi Inst       Date:  2021-12-30

4.  Oxidative damage, aging and anti-aging strategies.

Authors:  Ronny Haenold; D Mokhtar Wassef; Stefan H Heinemann; Toshinori Hoshi
Journal:  Age (Dordr)       Date:  2005-12-31

5.  Healthy aging - insights from Drosophila.

Authors:  Konstantin G Iliadi; David Knight; Gabrielle L Boulianne
Journal:  Front Physiol       Date:  2012-04-18       Impact factor: 4.566

6.  Amelioration of reproduction-associated oxidative stress in a viviparous insect is critical to prevent reproductive senescence.

Authors:  Veronika Michalkova; Joshua B Benoit; Geoffrey M Attardo; Jan Medlock; Serap Aksoy
Journal:  PLoS One       Date:  2014-04-24       Impact factor: 3.240

Review 7.  Effect of antioxidants supplementation on aging and longevity.

Authors:  Izabela Sadowska-Bartosz; Grzegorz Bartosz
Journal:  Biomed Res Int       Date:  2014-03-25       Impact factor: 3.411

8.  The genetic mechanisms of the influence of the light regime on the lifespan of Drosophila melanogaster.

Authors:  O A Shostal; A A Moskalev
Journal:  Front Genet       Date:  2013-01-25       Impact factor: 4.599

9.  In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury.

Authors:  Caterina Constantinou; Yiorgos Apidianakis; Nikolaos Psychogios; Valeria Righi; Michael N Mindrinos; Nadeem Khan; Harold M Swartz; Hazel H Szeto; Ronald G Tompkins; Laurence G Rahme; A Aria Tzika
Journal:  Int J Mol Med       Date:  2015-12-08       Impact factor: 4.101

10.  Modification of the head proteome of nurse honeybees (Apis mellifera) exposed to field-relevant doses of pesticides.

Authors:  Rodrigo Zaluski; Alis Correia Bittarello; José Cavalcante Souza Vieira; Camila Pereira Braga; Pedro de Magalhaes Padilha; Mileni da Silva Fernandes; Thaís de Souza Bovi; Ricardo de Oliveira Orsi
Journal:  Sci Rep       Date:  2020-02-10       Impact factor: 4.379
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