Literature DB >> 11409588

Quantitative bacillary response to treatment in Mycobacterium tuberculosis infected and M. africanum infected adults with pulmonary tuberculosis.

M L Joloba1, J L Johnson, A Namale, A Morrissey, A E Assegghai, S Rüsch-Gerdes, R D Mugerwa, J J Ellner, K D Eisenach.   

Abstract

Data regarding possible differences in microbiological response to therapy of disease caused by Mycobacterium tuberculosis and M. africanum are limited. Presenting clinical characteristics and sputum bacillary load during standard short-course chemotherapy in patients with newly-diagnosed pulmonary tuberculosis due to M. tuberculosis (n = 7) and M. africanum (n = 6) were compared. Changes in sputum bacillary load were measured using quantitative acid-fast bacilli smears, colony forming unit assay, and time until positive culture in the BACTEC radiometric system. Presentation and response to short course chemotherapy were comparable between patients infected with M. tuberculosis and those infected with M. africanum.

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Year:  2001        PMID： 11409588

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN： 1027-3719            Impact factor:   2.373


  2 in total

1.  Mycobacterium africanum subtype II is associated with two distinct genotypes and is a major cause of human tuberculosis in Kampala, Uganda.

Authors:  S Niemann; S Rüsch-Gerdes; M L Joloba; C C Whalen; D Guwatudde; J J Ellner; K Eisenach; N Fumokong; J L Johnson; T Aisu; R D Mugerwa; A Okwera; S K Schwander
Journal:  J Clin Microbiol       Date:  2002-09       Impact factor: 5.948

2.  Mycobacterium africanum (Lineage 6) shows slower sputum smear conversion on tuberculosis treatment than Mycobacterium tuberculosis (Lineage 4) in Bamako, Mali.

Authors:  Bassirou Diarra; Mahamadou Kone; Antieme Combo Georges Togo; Yeya Dit Sadio Sarro; Aissata Boubakar Cisse; Amadou Somboro; Boureima Degoga; Mohamed Tolofoudie; Bourahima Kone; Moumine Sanogo; Bocar Baya; Ousmane Kodio; Mamoudou Maiga; Michael Belson; Susan Orsega; Meryam Krit; Sounkalo Dao; Ibrahim Izétiegouma Maiga; Robert L Murphy; Leen Rigouts; Seydou Doumbia; Souleymane Diallo; Bouke Catherine de Jong
Journal:  PLoS One       Date:  2018-12-12       Impact factor: 3.240
  2 in total

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