Literature DB >> 1140905

The effect of chronic lithium application on the mineral content of rat bone and soft tissues.

S Bellwinkel, A Schäfer, H Minne, R Ziegler.   

Abstract

Rats were treated with lithium chloride over 6 weeks. During the experiment, determinations of serum calcium, magnesium and phosphorus revealed no changes due to the therapy. Postmortem examinations of liver, skeletal muscle, and femur minerals as well as bone histology showed these organs to be unaffected by lithium application. Only body weight gain was in part increased by lithium.

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Year:  1975        PMID： 1140905     DOI： 10.1159/000468163

Source DB:  PubMed          Journal:  Int Pharmacopsychiatry        ISSN： 0020-8272


  3 in total

1.  Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice.

Authors:  Philippe Clément-Lacroix; Minrong Ai; Frederic Morvan; Sergio Roman-Roman; Béatrice Vayssière; Cecille Belleville; Kenneth Estrera; Matthew L Warman; Roland Baron; Georges Rawadi
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-17       Impact factor: 11.205

2.  Lithium inhibition of bone mineralization and osteoid formation.

Authors:  D T Baran; M P Schwartz; M A Bergfeld; S L Teitelbaum; E Slatopolsky; L V Avioli
Journal:  J Clin Invest       Date:  1978-06       Impact factor: 14.808

Review 3.  The Skeletal-Protecting Action and Mechanisms of Action for Mood-Stabilizing Drug Lithium Chloride: Current Evidence and Future Potential Research Areas.

Authors:  Sok Kuan Wong; Kok-Yong Chin; Soelaiman Ima-Nirwana
Journal:  Front Pharmacol       Date:  2020-04-07       Impact factor: 5.810
  3 in total

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