Literature DB >> 11406895

Methylphenidate for fatigue in advanced cancer: a prospective open-label pilot study.

N Sarhill1, D Walsh, K A Nelson, J Homsi, S LeGrand, M P Davis.   

Abstract

Psychostimulants such as methylphenidate are used for fatigue in cancer patients. We report a prospective, open-label, pilot study of the successful use of methylphenidate to treat fatigue in nine of 11 consecutive patients with advanced cancer. Seven had received radiation or chemotherapy, a median of three weeks (range from one to 30 weeks) prior to methylphenidate. A rapid onset of benefit was noted, even in the presence of mild anemia. Sedation and pain also improved in some. Only one patient had side effects severe enough to stop the medication.

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Year:  2001        PMID: 11406895     DOI: 10.1177/104990910101800310

Source DB:  PubMed          Journal:  Am J Hosp Palliat Care        ISSN: 1049-9091            Impact factor:   2.500


  23 in total

1.  Cancer fatigue--more data, less information?

Authors:  Susan B LeGrand
Journal:  Curr Oncol Rep       Date:  2002-07       Impact factor: 5.075

Review 2.  Cancer-related fatigue: an update.

Authors:  Amit Sood; Timothy J Moynihan
Journal:  Curr Oncol Rep       Date:  2005-07       Impact factor: 5.075

Review 3.  Methylphenidate for the treatment of depressive symptoms, including fatigue and apathy, in medically ill older adults and terminally ill adults.

Authors:  Susan E Hardy
Journal:  Am J Geriatr Pharmacother       Date:  2009-02

4.  [Modafinil for the treatment of cancer-related fatigue : an intervention study].

Authors:  S Wirz; J Nadstawek; K U Kühn; S Vater; U Junker; H C Wartenberg
Journal:  Schmerz       Date:  2010-12       Impact factor: 1.107

5.  Phase III, randomized, double-blind, placebo-controlled study of long-acting methylphenidate for cancer-related fatigue: North Central Cancer Treatment Group NCCTG-N05C7 trial.

Authors:  Amanda R Moraska; Amit Sood; Shaker R Dakhil; Jeff A Sloan; Debra Barton; Pamela J Atherton; Jason J Suh; Patricia C Griffin; David B Johnson; Aneela Ali; Peter T Silberstein; Steven F Duane; Charles L Loprinzi
Journal:  J Clin Oncol       Date:  2010-07-12       Impact factor: 44.544

Review 6.  Management of fatigue in cancer patients.

Authors:  Mellar P Davis; Dilara Khoshknabi; Guang H Yue
Journal:  Curr Pain Headache Rep       Date:  2006-08

7.  Fatigue in advanced cancer patients attending an outpatient palliative radiotherapy clinic as screened by the Edmonton Symptom Assessment System.

Authors:  Liang Zeng; Kaitlin Koo; Liying Zhang; Florencia Jon; Kristopher Dennis; Lori Holden; Janet Nguyen; May Tsao; Elizabeth Barnes; Cyril Danjoux; Arjun Sahgal; Edward Chow
Journal:  Support Care Cancer       Date:  2011-05-04       Impact factor: 3.603

8.  Cancer-Related Fatigue, Version 2.2015.

Authors:  Ann M Berger; Kathi Mooney; Amy Alvarez-Perez; William S Breitbart; Kristen M Carpenter; David Cella; Charles Cleeland; Efrat Dotan; Mario A Eisenberger; Carmen P Escalante; Paul B Jacobsen; Catherine Jankowski; Thomas LeBlanc; Jennifer A Ligibel; Elizabeth Trice Loggers; Belinda Mandrell; Barbara A Murphy; Oxana Palesh; William F Pirl; Steven C Plaxe; Michelle B Riba; Hope S Rugo; Carolina Salvador; Lynne I Wagner; Nina D Wagner-Johnston; Finly J Zachariah; Mary Anne Bergman; Courtney Smith
Journal:  J Natl Compr Canc Netw       Date:  2015-08       Impact factor: 11.908

Review 9.  Cancer-related fatigue: the approach and treatment.

Authors:  Carmen P Escalante; Ellen F Manzullo
Journal:  J Gen Intern Med       Date:  2009-11       Impact factor: 5.128

10.  Fatigue in cancer: a review of literature.

Authors:  Vijayakumar Narayanan; Cherian Koshy
Journal:  Indian J Palliat Care       Date:  2009-01
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