| Literature DB >> 11406857 |
I Berger1, C M Passreiter, A Cáceres, W Kubelka.
Abstract
Extracts, fractions and sesquiterpene lactones from Neurolaena lobata (L.) R. Br. (Asteraceae), a traditional medicinal plant from Guatemala, were tested in vitro against Leishmania spp. promastigotes, Trypanosoma cruzi trypomastigotes and epimastigotes and Trichomonas vaginalis trophozoites. The ethanol extract inhibited the parasite growth of L. mexicana, T. cruzi and T. vaginalis significantly. The pure germacranolides 1 and a mixture of 2 and 3, isolated from the ethonal extract, were highly active against L. mexicana and T. cruzi. Copyright 2001 John Wiley & Sons, Ltd.Entities:
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Year: 2001 PMID: 11406857 DOI: 10.1002/ptr.782
Source DB: PubMed Journal: Phytother Res ISSN: 0951-418X Impact factor: 5.878