| Literature DB >> 11406363 |
C M Lewis1, C Broussard, M J Czar, P L Schwartzberg.
Abstract
The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes containing LAT and SLP-76 in T cells, and BLNK/SLP-65 in B cells, which are required for activation of PLC-gamma and downstream pathways.Entities:
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Year: 2001 PMID: 11406363 DOI: 10.1016/s0952-7915(00)00221-1
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486