| Literature DB >> 11405726 |
F Pellarini1, D Pantarotto, T Da Ros, A Giangaspero, A Tossi, M Prato.
Abstract
[see structure]. A fullerene derivative containing a free amino group has been condensed with N-Fmoc-L-glutamic acid alpha-tert-butyl ester to give a C60-functionalized amino acid. The carboxylic end of this amino acid has been deprotected in acidic conditions, and the resulting acid has been used for solid-phase peptide synthesis. The final peptide, cleaved from the resin, was very soluble in water solutions and showed antimicrobial activity against two representative bacteria.Entities:
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Year: 2001 PMID： 11405726 DOI： 10.1021/ol015934m
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005