Literature DB >> 11405685

A thioester ligation approach to amphipathic bicyclic peptide library.

Y Sun1, G Lu, J P Tam.   

Abstract

An efficient approach to synthesize an amphipathic bicyclic peptide library from unprotected peptides is demonstrated through an on-resin intramolecular thioester ligation and an off-resin DMSO-mediated disulfide formation.

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Year:  2001        PMID： 11405685     DOI： 10.1021/ol015889i

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Ribosomal Synthesis of Natural-Product-Like Bicyclic Peptides in Escherichia coli.

Authors:  Nina Bionda; Rudi Fasan
Journal:  Chembiochem       Date:  2015-08-06       Impact factor: 3.164

Review 2.  Bicyclic Peptides as Next-Generation Therapeutics.

Authors:  Curran A Rhodes; Dehua Pei
Journal:  Chemistry       Date:  2017-07-27       Impact factor: 5.236

3.  Screening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonist.

Authors:  Wenlong Lian; Punit Upadhyaya; Curran A Rhodes; Yusen Liu; Dehua Pei
Journal:  J Am Chem Soc       Date:  2013-08-01       Impact factor: 15.419

4.  Macrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin.

Authors:  Xinya Hemu; James P Tam
Journal:  Curr Pharm Des       Date:  2017       Impact factor: 3.116

5.  Cell-permeable bicyclic peptide inhibitors against intracellular proteins.

Authors:  Wenlong Lian; Bisheng Jiang; Ziqing Qian; Dehua Pei
Journal:  J Am Chem Soc       Date:  2014-07-02       Impact factor: 15.419
  5 in total

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