Literature DB >> 11405641

Secretase targets for Alzheimer's disease: identification and therapeutic potential.

M S Wolfe1.   

Abstract

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Year:  2001        PMID： 11405641     DOI： 10.1021/jm0004897

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  18 in total

1.  Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.

Authors:  William P Esler; W Taylor Kimberly; Beth L Ostaszewski; Wenjuan Ye; Thekla S Diehl; Dennis J Selkoe; Michael S Wolfe
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-26       Impact factor: 11.205

2.  Investigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS.

Authors:  Eric Martineau; Janna M de Guzman; Lioudmila Rodionova; Xianqi Kong; Paul M Mayer; Ahmed M Aman
Journal:  J Am Soc Mass Spectrom       Date:  2010-05-31       Impact factor: 3.109

Review 3.  Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?

Authors:  Kawser Akter; Emily A Lanza; Stephen A Martin; Natalie Myronyuk; Melanie Rua; Robert B Raffa
Journal:  Br J Clin Pharmacol       Date:  2011-03       Impact factor: 4.335

4.  Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.

Authors:  Dehui Duan; Dina M Sigano; James A Kelley; Christopher C Lai; Nancy E Lewin; Noemi Kedei; Megan L Peach; Jeewoo Lee; Thushara P Abeyweera; Susan A Rotenberg; Hee Kim; Young Ho Kim; Saïd El Kazzouli; Jae-Uk Chung; Howard A Young; Matthew R Young; Alyson Baker; Nancy H Colburn; Adriana Haimovitz-Friedman; Jean-Philip Truman; Damon A Parrish; Jeffrey R Deschamps; Nicholas A Perry; Robert J Surawski; Peter M Blumberg; Victor E Marquez
Journal:  J Med Chem       Date:  2008-08-13       Impact factor: 7.446

5.  Rationalizing lead optimization by consensus 2D- CoMFA CoMSIA GRIND (3D) QSAR guided fragment hopping in search of γ-secretase inhibitors.

Authors:  Prabu Manoharan; Nanda Ghoshal
Journal:  Mol Divers       Date:  2012-08-14       Impact factor: 2.943

Review 6.  The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism.

Authors:  Jie Shen; Raymond J Kelleher
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-29       Impact factor: 11.205

7.  Ddi1-like protein from Leishmania major is an active aspartyl proteinase.

Authors:  María J Perteguer; Paulino Gómez-Puertas; Carmen Cañavate; Francehuli Dagger; Teresa Gárate; Elizabeth Valdivieso
Journal:  Cell Stress Chaperones       Date:  2012-08-30       Impact factor: 3.667

8.  Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40.

Authors:  Cindy M Sondag; Colin K Combs
Journal:  J Neuroinflammation       Date:  2010-03-19       Impact factor: 8.322

Review 9.  BACE and gamma-secretase characterization and their sorting as therapeutic targets to reduce amyloidogenesis.

Authors:  Neville Marks; Martin J Berg
Journal:  Neurochem Res       Date:  2009-09-17       Impact factor: 3.996

10.  Protein flexibility in virtual screening: the BACE-1 case study.

Authors:  Sandro Cosconati; Luciana Marinelli; Francesco Saverio Di Leva; Valeria La Pietra; Angela De Simone; Francesca Mancini; Vincenza Andrisano; Ettore Novellino; David S Goodsell; Arthur J Olson
Journal:  J Chem Inf Model       Date:  2012-10-08       Impact factor: 4.956
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