M Amatsu1, M Mohri, M Kinishi. 1. Department of Otorhinolaryngology-Head & Neck Surgery, Kobe University School of Medicine, Kobe, Japan.
Abstract
OBJECTIVES: To clarify the efficacy of dissection of retropharyngeal lymph nodes (RPLNs) in the surgical treatment of carcinoma of the hypopharynx and cervical esophagus. STUDY DESIGN: We started planned dissection of the RPLN during initial radical surgery in patients with squamous cell carcinoma of the hypopharynx or the cervical esophagus in 1988. Until 1997, we performed this procedure as a standard operation in 82 consecutive patients. METHODS: Mortality resulting from RPLN metastasis was compared between 82 patients who underwent RPLN dissection and 69 patients who did not undergo the procedure. RESULTS: Of 82 patients, 16 patients (20%) had positive RPLNs. These patients were at high risk of recurrence unless the node(s) were dissected. Although RPLN dissection did not improve the cumulative 5-year survival rate, it significantly decreased the number of patients who died of RPLN metastasis (chi2 = 3.68, P <.1). Four of the 16 patients who had positive RPLNs survived without any recurrence. CONCLUSION: Bilateral dissection of the RPLN during initial surgery is highly recommended in every surgical case of carcinoma of the hypopharynx and cervical esophagus.
OBJECTIVES: To clarify the efficacy of dissection of retropharyngeal lymph nodes (RPLNs) in the surgical treatment of carcinoma of the hypopharynx and cervical esophagus. STUDY DESIGN: We started planned dissection of the RPLN during initial radical surgery in patients with squamous cell carcinoma of the hypopharynx or the cervical esophagus in 1988. Until 1997, we performed this procedure as a standard operation in 82 consecutive patients. METHODS: Mortality resulting from RPLN metastasis was compared between 82 patients who underwent RPLN dissection and 69 patients who did not undergo the procedure. RESULTS: Of 82 patients, 16 patients (20%) had positive RPLNs. These patients were at high risk of recurrence unless the node(s) were dissected. Although RPLN dissection did not improve the cumulative 5-year survival rate, it significantly decreased the number of patients who died of RPLN metastasis (chi2 = 3.68, P <.1). Four of the 16 patients who had positive RPLNs survived without any recurrence. CONCLUSION: Bilateral dissection of the RPLN during initial surgery is highly recommended in every surgical case of carcinoma of the hypopharynx and cervical esophagus.
Authors: Hae Sang Park; Eun Jae Chung; Min Woo Park; Sung Hee Bae; Soo Yeon Jung; Han Su Kim; Dae Young Yoon; Young Soo Rho Journal: Eur Arch Otorhinolaryngol Date: 2016-04-28 Impact factor: 2.503
Authors: George Garas; Nick J Roland; Jeffrey Lancaster; Matthew Zammit; Victoria A Manon; Katharine Davies; Terry M Jones; Mriganka De; Floyd C Holsinger; Robin J D Prestwich; Jason C Fleming Journal: Ann Surg Oncol Date: 2022-07-16 Impact factor: 4.339
Authors: Marcie Tauzin; Amy Rabalais; Joseph L Hagan; Charles G Wood; Robert L Ferris; Rohan R Walvekar Journal: World J Surg Oncol Date: 2010-08-16 Impact factor: 2.754
Authors: H Hakan Coskun; Jesus E Medina; K Thomas Robbins; Carl E Silver; Primož Strojan; Afshin Teymoortash; Phillip K Pellitteri; Juan P Rodrigo; Sandro J Stoeckli; Ashok R Shaha; Carlos Suárez; Dana M Hartl; Remco de Bree; Robert P Takes; Marc Hamoir; Karen T Pitman; Alessandra Rinaldo; Alfio Ferlito Journal: Head Neck Date: 2014-06-30 Impact factor: 3.147
Authors: Nam P Nguyen; Jacqueline Vock; Vincent Vinh-Hung; Fabio Almeida; Lars Ewell; Michael Betz; Siyoung Jang; Richard A Vo; Suresh Dutta; Juan Godinez; Ulf Karlsson; Alexander Chi Journal: BMC Cancer Date: 2012-06-18 Impact factor: 4.430