Literature DB >> 11404089

The expression pattern of tomoregulin-1 in urodele limb regeneration and mouse limb development.

S Morais da Silva1, P B Gates, D W Eib, G J Martens, J P Brockes.   

Abstract

Tomoregulin-1 (TMEFF1) was first identified as a gene implicated in pituitary secretion in Xenopus laevis. The predicted structure of TMEFF1 is that of a transmembrane protein with a highly conserved cytoplasmic tail, two follistatin domains and one modified EGF domain in its extracellular region. We report the cloning of the newt orthologue, and show that the expression of TMEFF1 is upregulated in the blastema during limb regeneration, and is also expressed in mouse embryonic limb development.

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Year:  2001        PMID: 11404089     DOI: 10.1016/s0925-4773(01)00362-8

Source DB:  PubMed          Journal:  Mech Dev        ISSN: 0925-4773            Impact factor:   1.882


  3 in total

1.  Analysis of TMEFF2 allografts and transgenic mouse models reveals roles in prostate regeneration and cancer.

Authors:  Joshua M Corbin; Ryan F Overcash; Jonathan D Wren; Anita Coburn; Greg J Tipton; Jennifer A Ezzell; Kirk K McNaughton; Kar-Ming Fung; Stanley D Kosanke; Maria J Ruiz-Echevarria
Journal:  Prostate       Date:  2015-09-29       Impact factor: 4.104

2.  Tomoregulin-1 prevents cardiac hypertrophy after pressure overload in mice by inhibiting TAK1-JNK pathways.

Authors:  Dan Bao; Dan Lu; Ning Liu; Wei Dong; Ying-Dong Lu; Chuan Qin; Lian-Feng Zhang
Journal:  Dis Model Mech       Date:  2015-06-18       Impact factor: 5.758

3.  TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.

Authors:  Xin Nie; Cong Liu; Qian Guo; Ming-Jun Zheng; Ling-Ling Gao; Xiao Li; Da-Wo Liu; Lian-Cheng Zhu; Juan-Juan Liu; Bei Lin
Journal:  Cancer Manag Res       Date:  2019-01-17       Impact factor: 3.989

  3 in total

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