Literature DB >> 11403493

Investigation of pharmaceutical high-performance liquid chromatography assay bias using experimental design.

J G Chen1, K Glancy, X Chen, M Alasandro.   

Abstract

This article presents a systematic approach to investigate, document, and eliminate pharmaceutical HPLC assay bias using experimental design. This is the first article to describe the application of experimental design in the area of assay bias. It is found that both formulation and analytical variables can contribute to pharmaceutical HPLC assay bias using model compounds and formulations.

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Year:  2001        PMID: 11403493     DOI: 10.1016/s0021-9673(01)00670-7

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  1 in total

1.  Development and Validation of an HPLC Method Using an Experimental Design for Analysis of Amlodipine Besylate and Enalapril Maleate in a Fixed-dose Combination

Authors:  Diren Sarısaltık Yaşın; Alev Arslantürk Bingül; Alptuğ Karaküçük; Zeynep Şafak Teksin
Journal:  Turk J Pharm Sci       Date:  2021-06-18
  1 in total

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