Literature DB >> 11403230

Evidence for a correlation between antibody-dependent cellular cytotoxicity-mediating anti-HIV-1 antibodies and prognostic predictors of HIV infection.

R Ahmad1, S T Sindhu, E Toma, R Morisset, J Vincelette, J Menezes, A Ahmad.   

Abstract

Using our gp120/41-expressing, NK cell activity-resistant CEM.NKR cell clones as targets in HIV-1-specific antibody-dependent cellular cytotoxicity (ADCC) assays, we demonstrate here that the serum titers of anti-HIV-1 ADCC antibodies bear a significant (P < 0.05) positive correlation with the peripheral blood CD4+ T cell counts and a negative one with the number of copies of HIV-1 RNA in the plasma of HIV-infected individuals. These findings underscore the importance of these antibodies as a protective immune parameter in these infections.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11403230     DOI： 10.1023/a:1011087132180

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  40 in total

1.  The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells.

Authors:  G B Cohen; R T Gandhi; D M Davis; O Mandelboim; B K Chen; J L Strominger; D Baltimore
Journal:  Immunity       Date:  1999-06       Impact factor: 31.745

2.  Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo.

Authors:  P Poignard; R Sabbe; G R Picchio; M Wang; R J Gulizia; H Katinger; P W Parren; D E Mosier; D R Burton
Journal:  Immunity       Date:  1999-04       Impact factor: 31.745

Review 3.  Cellular and humoral antigenic epitopes in HIV and SIV.

Authors:  D F Nixon; K Broliden; G Ogg; P A Broliden
Journal:  Immunology       Date:  1992-08       Impact factor: 7.397

4.  Antibody-dependent cellular cytotoxicity against HIV-1 in sera of immunized chimpanzees.

Authors:  M Belo; M Yagello; M Girard; R Greenlee; A Deslandres; F Barré-Sinoussi; J C Gluckman
Journal:  AIDS       Date:  1991-02       Impact factor: 4.177

5.  Lysis of uninfected HIV-1 gp120-coated peripheral blood-derived T lymphocytes by monocyte-mediated antibody-dependent cellular cytotoxicity.

Authors:  D Hober; A Jewett; B Bonavida
Journal:  FEMS Immunol Med Microbiol       Date:  1995-01

Review 6.  Antibody-dependent cellular cytotoxicity in HIV infections.

Authors:  A Ahmad; J Menezes
Journal:  FASEB J       Date:  1996-02       Impact factor: 5.191

7.  Antibody-dependent cellular cytotoxicity-inducing antibodies against human immunodeficiency virus. Presence at different clinical stages.

Authors:  K Ljunggren; B Böttiger; G Biberfeld; A Karlson; E M Fenyö; M Jondal
Journal:  J Immunol       Date:  1987-10-01       Impact factor: 5.422

8.  Cellular anti-GP120 cytolytic reactivities in HIV-1 seropositive individuals.

Authors:  K J Weinhold; H K Lyerly; T J Matthews; D S Tyler; P M Ahearne; K C Stine; A J Langlois; D T Durack; D P Bolognesi
Journal:  Lancet       Date:  1988-04-23       Impact factor: 79.321

9.  Evidence for a defect of antibody-dependent cellular cytotoxic (ADCC) effector function and anti-HIV gp120/41-specific ADCC-mediating antibody titres in HIV-infected individuals.

Authors:  A Ahmad; R Morisset; R Thomas; J Menezes
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1994-05

Review 10.  Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases.

Authors:  B G Brenner; A Dascal; R G Margolese; M A Wainberg
Journal:  J Leukoc Biol       Date:  1989-07       Impact factor: 4.962
View more
  68 in total

1.  Determining the phagocytic activity of clinical antibody samples.

Authors:  Elizabeth G McAndrew; Anne-Sophie Dugast; Anna F Licht; Justin R Eusebio; Galit Alter; Margaret E Ackerman
Journal:  J Vis Exp       Date:  2011-11-30       Impact factor: 1.355

2.  Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers.

Authors:  Jennifer I Lai; Anna F Licht; Anne-Sophie Dugast; Todd Suscovich; Ickwon Choi; Chris Bailey-Kellogg; Galit Alter; Margaret E Ackerman
Journal:  J Virol       Date:  2013-12-18       Impact factor: 5.103

3.  Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity.

Authors:  Amy W Chung; Jenniffer M Mabuka; Bongiwe Ndlovu; Anna Licht; Hannah Robinson; Yathisha Ramlakhan; Musie Ghebremichael; Tarylee Reddy; Philip J R Goulder; Bruce D Walker; Thumbi Ndung'u; Galit Alter
Journal:  AIDS       Date:  2018-06-19       Impact factor: 4.177

4.  Differential Effect of Mucosal NKp44+ Innate Lymphoid Cells and Δγ Cells on Simian Immunodeficiency Virus Infection Outcome in Rhesus Macaques.

Authors:  Mohammad Arif Rahman; Eun-Ju Ko; Gospel Enyindah-Asonye; Sabrina Helmold Hait; Christopher Hogge; Ruth Hunegnaw; David J Venzon; Tanya Hoang; Marjorie Robert-Guroff
Journal:  J Immunol       Date:  2019-09-25       Impact factor: 5.422

5.  Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1.

Authors:  Rada Ellegård; Elisa Crisci; Jonas Andersson; Esaki M Shankar; Sofia Nyström; Jorma Hinkula; Marie Larsson
Journal:  J Immunol       Date:  2015-07-08       Impact factor: 5.422

6.  Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC.

Authors:  Karen V Kibler; Benedikt Asbach; Beatriz Perdiguero; Juan García-Arriaza; Nicole L Yates; Robert Parks; Sherry Stanfield-Oakley; Guido Ferrari; David C Montefiori; Georgia D Tomaras; Mario Roederer; Kathryn E Foulds; Donald N Forthal; Michael S Seaman; Steve Self; Raphael Gottardo; Sanjay Phogat; James Tartaglia; Susan Barnett; Anthony D Cristillo; Deborah Weiss; Lindsey Galmin; Song Ding; Jonathan L Heeney; Mariano Esteban; Ralf Wagner; Giuseppe Pantaleo; Bertram L Jacobs
Journal:  J Virol       Date:  2019-01-17       Impact factor: 5.103

7.  Specific antibody-dependent cellular cytotoxicity responses associated with slow progression of HIV infection.

Authors:  Leia H Wren; Amy W Chung; Gamze Isitman; Anthony D Kelleher; Matthew S Parsons; Janaki Amin; David A Cooper; Ivan Stratov; Marjon Navis; Stephen J Kent
Journal:  Immunology       Date:  2013-02       Impact factor: 7.397

8.  Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b.

Authors:  Margaret E Ackerman; Anne-Sophie Dugast; Elizabeth G McAndrew; Stephen Tsoukas; Anna F Licht; Darrell J Irvine; Galit Alter
Journal:  J Virol       Date:  2013-03-06       Impact factor: 5.103

9.  Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques.

Authors:  Peng Xiao; Jun Zhao; L Jean Patterson; Egidio Brocca-Cofano; David Venzon; Pamela A Kozlowski; Rachmat Hidajat; Thorsten Demberg; Marjorie Robert-Guroff
Journal:  J Virol       Date:  2010-05-05       Impact factor: 5.103

10.  Robust NK cell-mediated human immunodeficiency virus (HIV)-specific antibody-dependent responses in HIV-infected subjects.

Authors:  Ivan Stratov; Amy Chung; Stephen J Kent
Journal:  J Virol       Date:  2008-03-19       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.