Literature DB >> 11401311

Proteolysis-inducing factor is expressed in tumours of patients with gastrointestinal cancers and correlates with weight loss.

R Cabal-Manzano1, P Bhargava, A Torres-Duarte, J Marshall, P Bhargava, I W Wainer.   

Abstract

Proteolysis-inducing factor (PIF), a novel cachectic factor, is detectable in the urine of cancer patients experiencing weight loss. We report the expression of PIF in gastrointestinal cancers, and a correlation between PIF expression in tumours, its detection in urine and weight-loss. These data provide the first direct evidence that tumours are the source of PIF in humans. Copyright 2001 Cancer Research Campaign.

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Year:  2001        PMID： 11401311      PMCID： PMC2363676          DOI： 10.1054/bjoc.2001.1830

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  20 in total

Review 1.  Anorexia-Cachexia syndrome in cancer: implications of the ubiquitin-proteasome pathway.

Authors:  Carlos Camps; Vega Iranzo; Roy M Bremnes; Rafael Sirera
Journal:  Support Care Cancer       Date:  2006-07-04       Impact factor: 3.603

2.  Understanding tumor anabolism and patient catabolism in cancer-associated cachexia.

Authors:  Alejandro Schcolnik-Cabrera; Alma Chávez-Blanco; Guadalupe Domínguez-Gómez; Alfonso Dueñas-González
Journal:  Am J Cancer Res       Date:  2017-05-01       Impact factor: 6.166

Review 3.  Clinical Factors as a Component of the Personalized Treatment Approach to Advanced Pancreatic Cancer: a Systematic Literature Review.

Authors:  William Paul Skelton; Hiral Parekh; Jason S Starr; Jose Trevino; Jessica Cioffi; Steven Hughes; Thomas J George
Journal:  J Gastrointest Cancer       Date:  2018-03

4.  The survival-promoting peptide Y-P30 enhances binding of pleiotrophin to syndecan-2 and -3 and supports its neuritogenic activity.

Authors:  Peter Landgraf; Petra Wahle; Hans-Christian Pape; Eckart D Gundelfinger; Michael R Kreutz
Journal:  J Biol Chem       Date:  2008-07-03       Impact factor: 5.157

5.  Recombinant human erythropoietin attenuates weight loss in a murine cancer cachexia model.

Authors:  H K van Halteren; G P A Bongaerts; C A M Verhagen; Y J L Kamm; J L Willems; G J Grutters; J P Koopman; D J Th Wagener
Journal:  J Cancer Res Clin Oncol       Date:  2004-01-27       Impact factor: 4.553

6.  Attenuation of muscle atrophy by an N-terminal peptide of the receptor for proteolysis-inducing factor (PIF).

Authors:  K A Mirza; S M Wyke; M J Tisdale
Journal:  Br J Cancer       Date:  2011-06-14       Impact factor: 7.640

7.  The presence of the proteolysis-inducing factor in urine does not predict the malignancy of a pancreatic tumour.

Authors:  Niels Teich; Jörg Kleeff; Herbert Lochs; Joachim Mössner; Volker Keim; Helmut Friess; Johann Ockenga
Journal:  BMC Gastroenterol       Date:  2005-06-21       Impact factor: 3.067

Review 8.  Non-surgical oncology - Guidelines on Parenteral Nutrition, Chapter 19.

Authors:  J Arends; G Zuercher; A Dossett; R Fietkau; M Hug; I Schmid; E Shang; A Zander
Journal:  Ger Med Sci       Date:  2009-11-18

9.  Metabolic and morphological alterations induced by proteolysis-inducing factor from Walker tumour-bearing rats in C2C12 myotubes.

Authors:  Claudia L Yano; Gislaine Ventrucci; William N Field; Michael J Tisdale; Maria Cristina C Gomes-Marcondes
Journal:  BMC Cancer       Date:  2008-01-28       Impact factor: 4.430

10.  Cancer cachexia.

Authors:  Marcus E Martignoni; Philipp Kunze; Helmut Friess
Journal:  Mol Cancer       Date:  2003-11-05       Impact factor: 27.401
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