| Literature DB >> 11399435 |
S Alagarsamy1, S D Sorensen, P J Conn.
Abstract
Recent studies aimed at identifying the mechanisms that regulate the signaling of metabotropic glutamate receptors (mGluRs) have revealed that both protein kinase and protein phosphatase activity are important in directly modulating mGluR function. The inter-relationship between phosphorylation and dephosphorylation of mGluRs seems to be an important determinant in regulating mGluR function and the subsequent neuromodulatory events elicited by activation of mGluRs.Mesh:
Substances:
Year: 2001 PMID: 11399435 DOI: 10.1016/s0959-4388(00)00219-1
Source DB: PubMed Journal: Curr Opin Neurobiol ISSN: 0959-4388 Impact factor: 6.627