Literature DB >> 11395864

Production of transgenic rodents by the microinjection of cloned DNA into fertilized one-cell eggs.

S L Si-Hoe1, S Wells, D Murphy.   

Abstract

Transgenic technologies that enable rapid movement between genotype and phenotype through specific loss-of-function, overexpression, or misexpression phenotypes will be crucial in the elucidation of gene sequences emerging from genome projects. This article describes detailed procedures for the generation of transgenic mice and rats by the injection of cloned DNA into the pronuclei of fertilized one-cell eggs.

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Year:  2001        PMID： 11395864     DOI： 10.1385/MB:17:2:151

Source DB:  PubMed          Journal:  Mol Biotechnol        ISSN： 1073-6085            Impact factor:   2.695


  68 in total

1.  Enhancement of TBP binding by activators and general transcription factors.

Authors:  X Y Li; A Virbasius; X Zhu; M R Green
Journal:  Nature       Date:  1999-06-10       Impact factor: 49.962

2.  A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

Authors:  W C Forrester; E Epner; M C Driscoll; T Enver; M Brice; T Papayannopoulou; M Groudine
Journal:  Genes Dev       Date:  1990-10       Impact factor: 11.361

Review 3.  Dynamic chromatin: the regulatory domain organization of eukaryotic gene loci.

Authors:  C Bonifer; A Hecht; H Saueressig; D M Winter; A E Sippel
Journal:  J Cell Biochem       Date:  1991-10       Impact factor: 4.429

4.  Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.

Authors:  M Schinke; O Baltatu; M Böhm; J Peters; W Rascher; G Bricca; A Lippoldt; D Ganten; M Bader
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

5.  A dominant phenocopy of hypopituitarism in transgenic mice resulting from central nervous system synthesis of human growth hormone.

Authors:  P G Hollingshead; L Martin; S L Pitts; T A Stewart
Journal:  Endocrinology       Date:  1989-09       Impact factor: 4.736

6.  Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

Authors:  R L Brinster; H Y Chen; M E Trumbauer; M K Yagle; R D Palmiter
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

7.  Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes.

Authors:  R D Palmiter; R L Brinster; R E Hammer; M E Trumbauer; M G Rosenfeld; N C Birnberg; R M Evans
Journal:  Nature       Date:  1982-12-16       Impact factor: 49.962

8.  DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression.

Authors:  P Fraser; J Hurst; P Collis; F Grosveld
Journal:  Nucleic Acids Res       Date:  1990-06-25       Impact factor: 16.971

9.  Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs.

Authors:  R L Brinster; H Y Chen; M Trumbauer; A W Senear; R Warren; R D Palmiter
Journal:  Cell       Date:  1981-11       Impact factor: 41.582

10.  Position-independent, high-level expression of the human beta-globin gene in transgenic mice.

Authors:  F Grosveld; G B van Assendelft; D R Greaves; G Kollias
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582
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  2 in total

1.  CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos.

Authors:  Yanjiao Shao; Yuting Guan; Liren Wang; Zhongwei Qiu; Meizhen Liu; Yuting Chen; Lijuan Wu; Yongmei Li; Xueyun Ma; Mingyao Liu; Dali Li
Journal:  Nat Protoc       Date:  2014-09-25       Impact factor: 13.491

2.  PhiC31-based Site-Specific Transgenesis System for Production of Transgenic Bovine Embryos by Somatic Cell Nuclear Transfer and Intracytoplasmic Sperm Injection.

Authors:  Mohammad Hadi Sekhavati; Sayed Morteza Hosseini; Mojtaba Tahmoorespur; Kamran Ghaedi; Farnoosh Jafarpour; Mehdi Hajian; Kyanoosh Dormiani; Mohammad Hossain Nasr-Esfahani
Journal:  Cell J       Date:  2017-12-01       Impact factor: 2.479
  2 in total

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