Literature DB >> 11395258

Anti-inflammatory activity of Syzygium cumini bark.

S Muruganandan1, K Srinivasan, S Chandra, S K Tandan, J Lal, V Raviprakash.   

Abstract

The ethanolic extract of the bark of Syzygium cumini was investigated for its anti-inflammatory activity in animal models. The extract did not show any sign of toxicity up to a dose of 10.125 g/kg, p.o. in mice. Significant anti-inflammatory activity was observed in carrageenin (acute), kaolin-carrageenin (subacute), formaldehyde (subacute)-induced paw oedema and cotton pellet granuloma (chronic) tests in rats. The extract did not induce any gastric lesion in both acute and chronic ulcerogenic tests in rats. Thus, the present study demonstrated that S. cumini bark extract has a potent anti-inflammatory action against different phases of inflammation without any side effect on gastric mucosa.

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Year:  2001        PMID: 11395258     DOI: 10.1016/s0367-326x(00)00325-7

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  17 in total

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Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

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Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2010-12-08       Impact factor: 3.000

4.  An aqueous extract of Syzygium cumini protects against kainate-induced status epilepticus and amnesia: evidence for antioxidant and anti-inflammatory intervention.

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Journal:  Metab Brain Dis       Date:  2022-08-02       Impact factor: 3.655

5.  Vibriocidal activity of certain medicinal plants used in Indian folklore medicine by tribals of Mahakoshal region of central India.

Authors:  Anjana Sharma; Virendra Kumar Patel; Animesh Navin Chaturvedi
Journal:  Indian J Pharmacol       Date:  2009-06       Impact factor: 1.200

Review 6.  Syzygium cumini (L.) Skeels: a review of its phytochemical constituents and traditional uses.

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Journal:  Asian Pac J Trop Biomed       Date:  2012-03

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Journal:  J Physiol Biochem       Date:  2012-07-14       Impact factor: 4.158

8.  Evaluation of antioxidant and anticancer properties of the seed extracts of Syzygium fruticosum Roxb. growing in Rajshahi, Bangladesh.

Authors:  Shafiqul Islam; Samima Nasrin; Muhammad Ali Khan; A S M Sakhawat Hossain; Farhadul Islam; Proma Khandokhar; M Nurul Haque Mollah; Mamunur Rashid; Golam Sadik; Md Aziz Abdur Rahman; A H M Khurshid Alam
Journal:  BMC Complement Altern Med       Date:  2013-06-22       Impact factor: 3.659

9.  Syzygium cumini inhibits growth and induces apoptosis in cervical cancer cell lines: a primary study.

Authors:  D Barh; G Viswanathan
Journal:  Ecancermedicalscience       Date:  2008-08-21

10.  Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana.

Authors:  Amany Hamouda Mahmoud; Mamdouh Nabil Samy; Amira Samir Wanas; Mohamed Salah Kamel
Journal:  Iran J Basic Med Sci       Date:  2021-05       Impact factor: 2.699

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