Literature DB >> 11395256

Antinociceptive activity of Zizyphus spina-christi root bark extract.

B Adzu1, S Amos, C Wambebe, K Gamaniel.   

Abstract

The antinociceptive effect of the aqueous extract of Zizyphus spina-christi root bark was investigated in mice and rats. Acetic acid-induced writhing, formalin and thermal (hot plate) tests were used. The extract (50 and 100 mg/kg, i.p.) showed a dose-dependent analgesic effect in all the tests used. Its i.p. LD50 in mice was 2236.07 mg/kg.

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Year:  2001        PMID： 11395256     DOI： 10.1016/s0367-326x(00)00289-6

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  16 in total

1.  Zizyphus spina-christi extract protects against aflatoxin B1-initiated hepatic carcinogenicity.

Authors:  Mosaad A Abdel-Wahhab; Enayat A Omara; Mona M Abdel-Galil; Nabila S Hassan; Somaia A Nada; Ataa Saeed; Magdy M el-Sayed
Journal:  Afr J Tradit Complement Altern Med       Date:  2007-02-16

Review 2.  Propolis: An update on its chemistry and pharmacological applications.

Authors:  Rajib Hossain; Cristina Quispe; Rasel Ahmed Khan; Abu Saim Mohammad Saikat; Pranta Ray; Damira Ongalbek; Balakyz Yeskaliyeva; Divya Jain; Antonella Smeriglio; Domenico Trombetta; Roghayeh Kiani; Farzad Kobarfard; Naheed Mojgani; Parvaneh Saffarian; Seyed Abdulmajid Ayatollahi; Chandan Sarkar; Mohammad Torequl Islam; Dılhun Keriman; Arserim Uçar; Miquel Martorell; Antoni Sureda; Gianfranco Pintus; Monica Butnariu; Javad Sharifi-Rad; William C Cho
Journal:  Chin Med       Date:  2022-08-26       Impact factor: 4.546

3.  Bilosomes as Promising Nanovesicular Carriers for Improved Transdermal Delivery: Construction, in vitro Optimization, ex vivo Permeation and in vivo Evaluation.

Authors:  Sadek Ahmed; Mohamed Aly Kassem; Sinar Sayed
Journal:  Int J Nanomedicine       Date:  2020-12-08

Review 4.  Pharmacological and phytochemical appraisal of selected medicinal plants from jordan with claimed antidiabetic activities.

Authors:  Fatma U Afifi; Violet Kasabri
Journal:  Sci Pharm       Date:  2013-10-15

5.  Immunomodulatory, Cytotoxicity, and Antioxidant Activities of Roots of Ziziphus mauritiana.

Authors:  Samina Afzal; Murium Batool; Bashir Ahmad Ch; Ashfaq Ahmad; Muhammad Uzair; Khurram Afzal
Journal:  Pharmacogn Mag       Date:  2017-07-11       Impact factor: 1.085

6.  Neurophysiological study on possible protective and therapeutic effects of Sidr (Zizyphus spina-christi L.) leaf extract in male albino rats treated with pentylenetetrazol.

Authors:  Abeer M Waggas; Reem H Al-Hasani
Journal:  Saudi J Biol Sci       Date:  2010-06-09       Impact factor: 4.219

7.  Analgesic and free radical scavenging activities of hydromethanolic extract of Crateva adansonii stem bark.

Authors:  Nkeiruka E Udeh; Samuel O Onoja
Journal:  J Intercult Ethnopharmacol       Date:  2015-05-08

8.  Pharmacological basis of the use of the root bark of Zizyphus nummularia Aubrev. (Rhamnaceae) as anti-inflammatory agent.

Authors:  Sarbani Dey Ray; Supratim Ray; Muhammad Zia-Ul-Haq; Vincenzo De Feo; Saikat Dewanjee
Journal:  BMC Complement Altern Med       Date:  2015-11-23       Impact factor: 3.659

9.  Effect of Polymers on the Physicochemical Properties and Biological Performance of Fenoprofen Calcium Dihydrate-Triacetyl-β-Cyclodextrin Complex.

Authors:  Hussein O Ammar; Tarek S Makram; Shaimaa Mosallam
Journal:  Pharmaceutics       Date:  2017-07-03       Impact factor: 6.321

Review 10.  Herbal Drugs from Sudan: Traditional Uses and Phytoconstituents.

Authors:  Mohamed Gamaleldin Elsadig Karar; Nikolai Kuhnert
Journal:  Pharmacogn Rev       Date:  2017 Jul-Dec
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