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Literature DB >> 1139496

Interpretation of the PPD skin test in BCG-vaccinated children.

Abstract

Skin testing with 5 tuberculin units (TU) of purified protein derivative (PPD) of tuberculin stabilized with polysorbate (Tween) 80 was done 3 months and 1 year after immunization with bacille Calmette-Guérin (BCG) vaccine in two groups of children: one group vaccinated at birth and another group at age 6 years. Interpretation of the PPD skin test with 5 TU is possible in children 1 year and older vaccinated with BCG at birth: if the diameter of induration is more than 10 to 12 mm the reaction cannot be ascribed to BCG vaccination and is highly suggestive of supervening infection with Mycobacterium tuberculosis or occasionally atypical mycobacteria. In contrast, the interpretation of a PPD test in children vaccinated at age 6 years is extremely difficult.

Entities: Chemical Disease Species

Mesh：

Substances：
BCG Vaccine

Year: 1975 PMID： 1139496 PMCID： PMC1956471

Source DB: PubMed Journal: Can Med Assoc J ISSN： 0008-4409 Impact factor: 8.262

6 in total

1. The trend of tuberculous infection among some Indian tribes and the influence of BCG vaccination on the tuberculin test.

Authors: J D ARONSON; H C TAYLOR
Journal: Am Rev Tuberc Date: 1955-07

2. The tuberculin test.

Authors: E M Sewell; D O'Hare; E L Kendig
Journal: Pediatrics Date: 1974-11 Impact factor: 7.124

3. Significance of the tuberculin reaction.

Authors: S Grzybowski; M T Brown
Journal: Can Med Assoc J Date: 1969-06-07 Impact factor: 8.262

4. Diagnostic and prognostic significance of the quantitative tuberculin tests. The influence of subclinical infections with atypical mycobacteria.

Authors: D T Smith
Journal: Ann Intern Med Date: 1967-11 Impact factor: 25.391

5. Tuberculin skin sensitivity following BCG vaccination with vaccines of high and low viable counts.

Authors: M J Ashley; C O Siebenmann
Journal: Can Med Assoc J Date: 1967-11-25 Impact factor: 8.262

6. The duration of BCG-induced tuberculin sensitivity in children, and its irrelevance for revaccination. Results of two 5-year prospective studies.

Authors: J Guld; H Waaler; T K Sundaresan; P C Kaufmann; H G ten Dam
Journal: Bull World Health Organ Date: 1968 Impact factor: 9.408

6 in total

Review 1. Tuberculosis: 10. Prevention.

Authors: D Menzies; T N Tannenbaum; J M FitzGerald
Journal: CMAJ Date: 1999-09-21 Impact factor: 8.262

Interpretation of the PPD skin test in BCG-vaccinated children.

1. The trend of tuberculous infection among some Indian tribes and the influence of BCG vaccination on the tuberculin test.

2. The tuberculin test.

3. Significance of the tuberculin reaction.

4. Diagnostic and prognostic significance of the quantitative tuberculin tests. The influence of subclinical infections with atypical mycobacteria.

5. Tuberculin skin sensitivity following BCG vaccination with vaccines of high and low viable counts.

6. The duration of BCG-induced tuberculin sensitivity in children, and its irrelevance for revaccination. Results of two 5-year prospective studies.

Review 1. Tuberculosis: 10. Prevention.

Review 2. Common bacterial infections in infancy and childhood. 1. Respiratory infections.

Review 3. Gamma Interferon Assays Used in the Diagnosis of Tuberculosis.

4. A meta-analysis of the effect of Bacille Calmette Guérin vaccination on tuberculin skin test measurements.

Review 5. Diagnosis of tuberculosis in children: increased need for better methods.

6. Tuberculin reactivity in United States and foreign-born Latinos: results of a community-based screening program.