Literature DB >> 11393401

Synthesis and properties of oligonucleotides containing 8-bromo-2'-deoxyguanosine.

C Fàbrega1, M J Macías, R Eritja.   

Abstract

The preparation of oligonucleotides containing 8-bromo-2'-deoxyguanosine is described. Substitution of G by 8-bromoguanine on an alternating CG decamer stabilizes the Z-form in such a way that the B-form was not observed. Melting temperatures showed that duplexes in which 8-bromo-2'-deoxyguanosine paired with natural bases were much less stable.

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Year:  2001        PMID： 11393401     DOI： 10.1081/ncn-100002085

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  4 in total

1.  Chemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation.

Authors:  Takashi Asahi; Hajime Kondo; Mitsuharu Masuda; Hoyoku Nishino; Yasuaki Aratani; Yuji Naito; Toshikazu Yoshikawa; Shinsuke Hisaka; Yoji Kato; Toshihiko Osawa
Journal:  J Biol Chem       Date:  2010-01-15       Impact factor: 5.157

2.  8-methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures.

Authors:  Antonella Virgilio; Veronica Esposito; Antonio Randazzo; Luciano Mayol; Aldo Galeone
Journal:  Nucleic Acids Res       Date:  2005-10-27       Impact factor: 16.971

3.  Hybridization Properties of RNA Containing 8-Methoxyguanosine and 8-Benzyloxyguanosine.

Authors:  Daniel Sylwester Baranowski; Weronika Kotkowiak; Ryszard Kierzek; Anna Pasternak
Journal:  PLoS One       Date:  2015-09-09       Impact factor: 3.240

4.  Identification of nucleobase chemical modifications that reduce the hepatotoxicity of gapmer antisense oligonucleotides.

Authors:  Tokuyuki Yoshida; Kunihiko Morihiro; Yuki Naito; Atsushi Mikami; Yuuya Kasahara; Takao Inoue; Satoshi Obika
Journal:  Nucleic Acids Res       Date:  2022-07-22       Impact factor: 19.160
  4 in total

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