Literature DB >> 11393117

Acute paraplegia in a patient with spinal tophi: a case report.

L C Wang1, Y C Hung, E J Lee, H H Chen.   

Abstract

A 28-year-old man with a 5-year history of gouty arthritis suffered from an acute episode of lower back pain. He visited a rehabilitative clinic and received physical therapy following his examination. Weakness and numbness of both lower legs developed rapidly after physical therapy. He was sent to our hospital with complete paralysis of both lower limbs and complete sensory loss below the umbilicus 3 hours after the physical therapy. No peripheral tophi were found. Myelography showed an extrinsic compression of the dura sac at T10. Emergency decompressive laminectomy of T9 to T11 was performed. During the surgery, caseous material was found deposited in the ligamentum flavum and the left T9 to T10 facet joint, with indentation of the dura sac. The pathologic diagnosis was spinal tophi. After surgery, the patient's neurologic function recovered rapidly. It was suspected that inappropriate physical therapy might have aggravated acute inflammation of spinal gout and resulted in a rapid deterioration of neurologic function. Though gout is a chronic medical disease, an acute attack of spinal gout may be disastrous and requires emergency neurosurgical intervention.

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Year:  2001        PMID: 11393117

Source DB:  PubMed          Journal:  J Formos Med Assoc        ISSN: 0929-6646            Impact factor:   3.282


  6 in total

Review 1.  Axial (spinal) gout.

Authors:  Elena Lumezanu; Rukmini Konatalapalli; Arthur Weinstein
Journal:  Curr Rheumatol Rep       Date:  2012-04       Impact factor: 4.592

2.  Thoracic spinal cord compression by extradural tophus: a case report and review of the literature.

Authors:  T Liu; H Liu; T Zhu
Journal:  Spinal Cord Ser Cases       Date:  2015-10-08

Review 3.  Gout in the Spine: Imaging, Diagnosis, and Outcomes.

Authors:  Michael Toprover; Svetlana Krasnokutsky; Michael H Pillinger
Journal:  Curr Rheumatol Rep       Date:  2015-12       Impact factor: 4.592

4.  Spinal gout: A review with case illustration.

Authors:  Hossein Elgafy; Xiaochen Liu; Joseph Herron
Journal:  World J Orthop       Date:  2016-11-18

Review 5.  Thoracic cord compression due to ligamentum flavum gouty tophus: a case report and literature review.

Authors:  Z-F Zheng; H-L Shi; Y Xing; D Li; J-Y Jia; S Lin
Journal:  Spinal Cord       Date:  2015-06-16       Impact factor: 2.772

6.  Thoracic gout tophus with abdominal wall protrusion: A case report.

Authors:  Yanbing Kao; Zhenyu Wang; Jiali Leng; Zhigang Qu; Xinming Zhuang; Hongyun Ma; Qingxu Song; Zijing Liu; Shuo Sun; Yi Liu
Journal:  Medicine (Baltimore)       Date:  2020-03       Impact factor: 1.889

  6 in total

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