| Literature DB >> 11392547 |
K W Woods1, R W McCroskey, M R Michaelides, C K Wada, K I Hulkower, R L Bell.
Abstract
The carboxyl group of the NSAID indomethacin was replaced with a variety of substituted thiazoles to obtain a series of potent, selective inhibitors of COX-2. Additional substitutions were made at the 1-position and 5-position of the indole of indomethacin.Entities:
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Year: 2001 PMID： 11392547 DOI： 10.1016/s0960-894x(01)00212-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823