Literature DB >> 11390946

Physiological properties of blood substitutes.

D R Spahn1, T Pasch.   

Abstract

Blood substitutes (modified hemoglobin solutions, perfluorocarbon emulsions) serve as artificial oxygen carriers and are alternatives to blood transfusions. Hemoglobin solutions mimic the sigmoidal oxygen dissociation curve of natural blood. Perfluorocarbon emulsions exhibit a linear relation between PO2 and dissolved oxygen. The most advanced substances may enter medicine in few years.

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Year:  2001        PMID： 11390946     DOI： 10.1152/physiologyonline.2001.16.1.38

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  3 in total

1.  Tissue Concentration of Dodecafluoropentane (DDFP) Following Repeated IV Administration in the New Zealand White Rabbit.

Authors:  Christine Arthur; Lin Song; William Culp; Aliza Brown; Michael Borrelli; Robert Skinner; Howard Hendrickson
Journal:  AAPS J       Date:  2016-12-27       Impact factor: 4.009

2.  Blood substitutes--the polyheme trials.

Authors:  Sameer S Apte
Journal:  Mcgill J Med       Date:  2008-01

3.  Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas.

Authors:  Lisa A Feldman; Marie-Sophie Fabre; Carole Grasso; Dana Reid; William C Broaddus; Gregory M Lanza; Bruce D Spiess; Joel R Garbow; Melanie J McConnell; Patries M Herst
Journal:  PLoS One       Date:  2017-09-05       Impact factor: 3.240
  3 in total

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